Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Microfluidic point-of-care diagnostics for multi-disease detection using optical techniques: a review

S Ahmadsaidulu, O Banik, P Kumar… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
The lifestyle of modern society is a major contributing factor for the majority of patients
suffering from more than one disease. To Screen and diagnose each of those diseases …

Highly sensitive and selective photoelectrochemical aptasensor for cancer biomarker CA125 based on AuNPs/GaN Schottky junction

D Hu, H Liang, X Wang, F Luo, B Qiu, Z Lin… - Analytical …, 2020 - ACS Publications
A gold nanoparticle (AuNPs)/gallium nitride (GaN) Schottky junction was fabricated by
growing AuNPs in situ on the surface of GaN and then etched by H2O2 to appropriate …

Detection of the ovarian cancer biomarker CA-125 using chemiluminescence resonance energy transfer to graphene quantum dots

I Al-Ogaidi, H Gou, ZP Aguilar, S Guo… - Chemical …, 2014 - pubs.rsc.org
An immunoassay has been developed for the detection of the ovarian cancer biomarker CA-
125 by utilizing the chemiluminescence resonance energy transfer to graphene quantum …

A sandwich electrochemical immunosensor based on MXene@ dual MOFs for detection of tumor marker CA125

L Qu, M Wu, L Zhao, J Li, H Pan - Microchimica Acta, 2023 - Springer
The detection signal of carbohydrate antigen 125 (CA125) can be quantitatively amplified
via the dual metal–organic framework (MOF) sandwich strategy. We propose a versatile …

Hierarchical gold nanostructures modified electrode for electrochemical detection of cancer antigen CA125

SR Torati, KCSB Kasturi, B Lim, CG Kim - Sensors and Actuators B …, 2017 - Elsevier
Gold nanostructures (GNs) modified electrode, which was fabricated by simple, cost–
effective one–step electrochemical technique, was used for the development of an …

Improved ELISA for tumor marker detection using electro-readout-mode based on label triggered degradation of methylene blue

D Zhang, W Li, Z Ma, H Han - Biosensors and Bioelectronics, 2019 - Elsevier
Enzyme-linked immunosorbent assay (ELISA), a gold-standard method for protein detection,
has been widely utilized in disease diagnosis. Nevertheless, the method is constrained by …

Properties of Anti-CA125 antibody layers on screen-printed carbon electrodes modified by gold and platinum nanostructures

A Baradoke, B Jose, R Pauliukaite, RJ Forster - Electrochimica Acta, 2019 - Elsevier
In antibody-based biosensors, the nature of the underlying electrode can significantly
influence the binding strength of capture antibodies, their association constant and stable …

Prereduction-promoted enhanced growth of silver nanoparticles for ultrasensitive colorimetric detection of alkaline phosphatase and carbohydrate antigen 125

J Gao, M Jia, Y Xu, J Zheng, N Shao, M Zhao - Talanta, 2018 - Elsevier
A highly sensitive colorimetric method for detection of alkaline phosphatase (ALP) and
carbohydrate antigen (CA125) was developed, which was achieved by ascorbic acid (AA) …

Gold nanoparticle enhanced hybridization chain reaction as a method for signal amplification. Application to electrochemical immunodetection of the ovarian cancer …

Y Nie, M Yang, Y Ding - Microchimica Acta, 2018 - Springer
The authors describe a method for enhancing the hybridization chain reaction (HCR) by
using gold nanoparticles (AuNPs). This can considerably improve the sensitivity of …