Transcription activation is an important checkpoint of regulation of gene expression which
occurs in response to different intracellular and extracellular signals. The key elements in …

Mycobacterium tuberculosis (MTB) is the main source of tuberculosis (TB), one of the oldest
known diseases in the human population. Despite the drug discovery efforts of past …

Transcription activation is a crucial step of regulation during transcription initiation and a
classic check point in response to different stimuli and stress factors. The Escherichia coli …

Emerging Mycobacterium tuberculosis (Mtb) resistant strains have continued to limit the
efficacies of existing antitubercular therapies. More specifically, mutations in the RNA …

The stringent response, which leads to persistence of nutrient-starved mycobacteria, is
induced by activation of the RelA/SpoT homolog (Rsh) upon entry of a deacylated-tRNA in a …

The control of nutrient availability is an essential ecological function of the host organism in
host-microbe systems. Although often overshadowed by macronutrients such as …

To better understand host–phage interactions and the genetic bases of phage resistance in
a model system relevant to potential phage therapy, we isolated several spontaneous …

tremendous volume of 3D structural details needs to be represented in a limited number of
2D figures, so an effective and clear illustration of protein structure is crucial. With various …

Summary 1 A protein model is built based on a final cryoelectron microscopy (EM) map (A)
and then presented. An overall structure is usually represented using secondary structure …

El texto que se pone a consideración del lector, en su edición digital, revisada y corregida,
ha sido preparado con fines académicos, para la formación de médicos veterinarios y/o …