Carotenoids represent a large class of terpenoids characterized by an extensively
conjugated polyene chain. The conjugation system imparts carotenoids with excellent light …

Plant terpenoids are among the most diverse group of naturally-occurring organic
compounds known, and several are used in contemporary consumer products. Terpene …

Processive DNA synthesis by the αεθ core of the Escherichia coli Pol III replicase requires it
to be bound to the β2 clamp via a site in the α polymerase subunit. How the ε proofreading …

Terpenoids are a diverse class of compounds with wide-ranging uses including as industrial
solvents, pharmaceuticals, and fragrances. Efforts to produce terpenoids sustainably by …

<? xm-replace_text {Heading}?> Abstract Prokaryotic organisms (archaea and eubacteria)
are found in all habitats where life exists on our planet. This would not be possible without …

Methyl erythritol phosphate (MEP) is the metabolite found in the MEP pathway for isoprenoid
biosynthesis, which is known to be utilized by plants, algae, and bacteria. In this study, an …

Malaria is a highly prevalent infectious disease caused by the Plasmodium parasite
transmitted through Anopheles mosquitoes, which poses a significant public health …

Monoterpenes are important components of plant essential oils and have long been used as
raw materials for spices and food flavorings. Litsea cubeba is an economically aromatic …

Deoxy-d-xylulose-5-phosphate reductoisomerase (DXR) is one of the key enzymes in the
MEP terpenoid biosynthetic pathway. It catalyzes the rate-limiting step of the pathway …

Fosmidomycin is a time-dependent nanomolar inhibitor of methylerythritol phosphate (MEP)
synthase, which is the enzyme that catalyzes the first committed step in the MEP pathway to …