[PDF][PDF] Liver macrophages: old dogmas and new insights

A Guillot, F Tacke - Hepatology communications, 2019 - Wiley Online Library
Inflammation is a hallmark of virtually all liver diseases, such as liver cancer, fibrosis,
nonalcoholic steatohepatitis, alcoholic liver disease, and cholangiopathies. Liver …

Bile acids and bile acid activated receptors in the treatment of Covid-19

S Fiorucci, G Urbani, M Biagioli, V Sepe… - Biochemical …, 2023 - Elsevier
Since its first outbreak in 2020, the pandemic caused by the Severe Acute Respiratory
Syndrome-Coronavirus-2 (SARS-CoV-2) has caused the death of almost 7 million people …

Gut microbiota-derived ursodeoxycholic acid alleviates low birth weight-induced colonic inflammation by enhancing M2 macrophage polarization

Y Pi, Y Wu, X Zhang, D Lu, D Han, J Zhao, X Zheng… - Microbiome, 2023 - Springer
Background Low birth weight (LBW) is associated with intestinal inflammation and dysbiosis
after birth. However, the underlying mechanism remains largely unknown. Objective In the …

Intestinal Collinsella may mitigate infection and exacerbation of COVID-19 by producing ursodeoxycholate

M Hirayama, H Nishiwaki, T Hamaguchi, M Ito… - PLoS …, 2021 - journals.plos.org
The mortality rates of COVID-19 vary widely across countries, but the underlying
mechanisms remain unelucidated. We aimed at the elucidation of relationship between gut …

Isolation of Aloe saponaria-Derived Extracellular Vesicles and Investigation of Their Potential for Chronic Wound Healing

M Kim, JH Park - Pharmaceutics, 2022 - mdpi.com
A chronic wound is caused by a failure to progress through the normal phases of wound
repair in an orderly and timely manner. To induce skin regeneration while inhibiting chronic …

Design, synthesis and evaluation of ursodeoxycholic acid-cinnamic acid hybrids as potential anti-inflammatory agents by inhibiting Akt/NF-κB and MAPK signaling …

X Li, Y Hu, B He, L Li, Y Tian, Y Xiao, H Shang… - European Journal of …, 2023 - Elsevier
A series of ursodeoxycholic acid (UDCA)-cinnamic acid hybrids were designed and
synthesized. The anti-inflammatory activity of these derivatives was screened through …

Anti-inflammatory effects of quercetin in a mouse model of MC903-induced atopic dermatitis

DD Hou, W Zhang, YL Gao, Y Sun, HX Wang… - International …, 2019 - Elsevier
In this study, the anti-inflammatory mechanisms of Quercetin (Que) on atopic dermatitis (AD)-
like skin lesions was examined. The left ear of mice was applied with MC903, followed by …

Ursodeoxycholic acid as a candidate therapeutic to alleviate and/or prevent COVID-19-associated cytokine storm

S Abdulrab, S Al-Maweri, E Halboub - Medical Hypotheses, 2020 - ncbi.nlm.nih.gov
Coronavirus disease 2019 (COVID-19), caused by novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has caused an unprecedented global public health crisis …

Гепатопротекторы

СВ Оковитый, ВА Приходько, НН Безбородкина… - 2022 - elibrary.ru
В настоящем издании проанализированы и систематизированы сведения по
клиническому применению лекарственных средств, для которых гепатотропное …

Endoplasmic reticulum stress and intestinal inflammation: a perilous union

SP Eugene, VS Reddy, J Trinath - Frontiers in Immunology, 2020 - frontiersin.org
The intestinal tract encompasses the largest mucosal surface fortified with a fine layer of
intestinal epithelial cells along with highly sophisticated network of the lamina propria …