Myocardial fibrosis refers to a variety of quantitative and qualitative changes in the interstitial
myocardial collagen network that occur in response to cardiac ischaemic insults, systemic …

Heart failure (HF) is a leading cause of morbidity and mortality in the United States. Despite
a number of important therapeutic advances for the treatment of symptomatic HF, 1 the …

The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

A recent trend has emerged that involves myocardial injection of biomaterials, containing
cells or acellular, following myocardial infarction (MI) to influence the remodeling response …

Congestive heart failure (HF) is a clinical syndrome, with hallmarks of fatigue and dyspnea,
that continues to be highly prevalent and morbid. Because of the growing burden of HF as …

Following myocardial infarction, nonischemic myocyte death results in infarct expansion,
myocardial loss, and ventricular dysfunction. Here, we demonstrate that a specific …

Ischemic mitral regurgitation (IMR) is a common complication of coronary artery disease and
is the focus of a rapidly increasing amount of research. Mechanistic studies have determined …

Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

Tagged MRI and finite-element (FE) analysis are valuable tools in analyzing cardiac
mechanics. To determine systolic material parameters in three-dimensional stress-strain …

Ventricular wall stress is believed to be responsible for many physical mechanisms taking
place in the human heart, including ventricular remodeling, which is frequently associated …