The epithelial–mesenchymal transition is essential in both embryonic development and the
progression of carcinomas. Wnt signaling and cadherin-mediated adhesion have been …

Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …

THE cytoplasmic proteins β-catenin of vertebrates and armadillo of Drosophila have two
functions: they link the cadherin cell-adhesion molecules to the cytoskeleton1–4, and they …

Pemphigus vulgaris (PV) is a life-threatening skin disease in which autoantibodies against a
keratinocyte cell surface 130 kd glycoprotein, PV antigen (PVA), cause loss of cell-cell …

This review addresses the cellular and molecular mechanisms of cadherin-based tissue
morphogenesis. Tissue physiology is profoundly influenced by the distinctive organizations …

Controlled regulation of cell proliferation and differentiation is essential for embryonic
development and requires the coordinated regulation of cell–cell adhesion and gene …

Molecular analysis of the cadherin-catenin complex elucidated the central role of β-catenin
in this adhesion complex, as it binds to the cytoplasmic domain of E-cadherin and to α …

For decades, developmental and cell biologists have been attracted by the idea that cell
adhesion molecules (CAMs) play a central role in the development and maintenance of …

Increasing attention has focused on the significance of RNA in sperm, in light of its
contribution to the birth and long-term health of a child, role in sperm function and diagnostic …

Spermatogenesis is an intriguing but complicated biological process. However, many
studies since the 1960s have focused either on the hormonal events of the hypothalamus …