Simple Summary Communication between cells helps tumors acquire resistance to
chemotherapy and makes the struggle against cancer more challenging. Tunneling …

Simple Summary Tunneling nanotubes (TNTs) are cytoplasmic channels which regulate the
contacts between cells and allow the transfer of several elements, including ions …

Estrogen receptor-positive (ER+) breast cancer commonly disseminates to bone marrow,
where interactions with mesenchymal stromal cells (MSCs) shape disease trajectory. We …

Intercellular communication is pivotal in various stages of cancer progression. For smart and
effective communication, cancer cells employ diverse modes of messaging that may be …

Tunneling nanotubes (TNTs) are thin membrane tubular structures that interconnect
physically separated cells. Growing evidence indicates that TNTs play unique roles in …

The hypothesis that pathogenic protein aggregates associated with neurodegenerative
diseases spread from cell-to-cell in the brain in a manner akin to infectious prions has …

Fifty-two years have passed since President Nixon launched the “War on Cancer”. Despite
unparalleled efforts and funds allocated worldwide, the outlined goals were not achieved …

Chemoresistance often complicates the management of cancer, as noted in the instance of
acute myeloid leukemia (AML). Mitochondrial function is considered important for the …

Astroglia play crucial neuroprotective roles by internalizing pathogenic aggregates and
facilitating their degradation. Here, we show that α-SYN protofibril-induced organelle …

COVID-19 pandemic situation has affected millions of people with tens of thousands of
deaths worldwide. Despite all efforts for finding drugs or vaccines, the key role for the …