The immune response involves a complex repertoire of innate and adaptive responses to
foreign agents in the organism. The present review focuses on the immune response to …

Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …

Snake venom metalloproteinases (SVMPs) are widely distributed in snake venoms and play
important roles in hemostatic disorders and local tissue damage that follows snakebite. The …

Background Snake venoms are complex mixtures of pharmacologically active proteins and
peptides which belong to a small number of superfamilies. Global cataloguing of the venom …

Metalloproteinases are abundant enzymes in crotaline and viperine snake venoms. They
are relevant in the pathophysiology of envenomation, being responsible for local and …

Local tissue damage, characterized by edema, hemorrhage and necrosis, is a common
consequence of envenoming by many vipers. We have investigated the contribution of …

Cerberus rynchops (dog-faced water snake) belongs to Homalopsidae of Colubroidea (rear-
fanged snakes). So far, venom compositions of snakes of the Homalopsidae family are not …

The inflammatory events induced by BaP1, a 22.7 kDa metalloproteinase isolated from
Bothrops asper snake venom, were studied. BaP1 ip injection in mice induced a marked …

The peptidomimetic hydroxamate metalloproteinase inhibitor batimastat (BB-94) was
assessed for its ability to neutralize the systemic effects (lethality, hemorrhage and …