Anti-inflammatory effect of selenium nanoparticles on the inflammation induced in irradiated rats

MA El-Ghazaly, N Fadel, E Rashed… - Canadian journal of …, 2017 - cdnsciencepub.com
Selenium (Se) has been reported to possess anti-inflammatory properties, but its
bioavailability and toxicity are considerable limiting factors. The present study aimed to …

Therapeutic potentials of silver nanoparticle complex of α-lipoic acid

L Ramachandran, CKK Nair - Nanomaterials and …, 2011 - journals.sagepub.com
Silver (SN) nanoparticles were re-dispersed in aqueous solution of Pluronic F127 and
complexed with the antioxidant, alpha-Lipoic acid (LA). The nanoparticle-LA complex (SN …

Early reoxygenation in tumors after irradiation: determining factors and consequences for radiotherapy regimens using daily multiple fractions

N Crokart, BF Jordan, C Baudelet, R Ansiaux… - International Journal of …, 2005 - Elsevier
Purpose: To characterize changes in the tumor microenvironment early after irradiation and
determine the factors responsible for early reoxygenation. Methods and Materials …

Tumor radiosensitization by antiinflammatory drugs: evidence for a new mechanism involving the oxygen effect

N Crokart, K Radermacher, BF Jordan, C Baudelet… - Cancer research, 2005 - AACR
We hypothesized that nonsteroidal antiinflammatory drugs (NSAIDs) might enhance tumor
radiosensitivity by increasing tumor oxygenation (pO2), via either a decrease in the …

Therapeutic effects of lornoxicam-loaded nanomicellar formula in experimental models of rheumatoid arthritis

HS Helmy, AE El-Sahar, RH Sayed… - International journal …, 2017 - Taylor & Francis
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease treated by
nonsteroidal anti-inflammatory drugs (NSAIDs) including lornoxicam (LX). Nanocarriers …

Ablative radiotherapy reprograms the tumor microenvironment of a pancreatic tumor in favoring the immune checkpoint blockade therapy

YH Lee, CF Yu, YC Yang, JH Hong… - International Journal of …, 2021 - mdpi.com
The low overall survival rate of patients with pancreatic cancer has driven research to seek a
new therapeutic protocol. Radiotherapy (RT) is frequently an option in the neoadjuvant or …

[HTML][HTML] Anti-inflammatory, analgesic and COX-2 inhibitory activity of novel thiadiazoles in irradiated rats

FA Ragab, HI Heiba, MG El-Gazzar… - … of Photochemistry and …, 2017 - Elsevier
In this work, novel series of pyran, thiophene and thienopyrimidine derivatives based on 2-
acetamide-thiadiazole scaffold were designed and synthesized for evaluation as selective …

Amelioration of adjuvant-induced arthritis by exposure to low dose gamma radiation and resveratrol administration in rats

MA El-Ghazaly, NA Fadel, DH Abdel-Naby… - … journal of radiation …, 2020 - Taylor & Francis
Purpose: Low dose radiation has been reported as an effective treatment for rheumatoid
arthritis via multiple dose exposures. The present study was designed to increase the …

Synthesis of novel thiadiazole derivatives as selective COX-2 inhibitors

FA Ragab, HI Heiba, MG El-Gazzar, SM Abou-Seri… - …, 2016 - pubs.rsc.org
A novel series of thiadiazole derivatives were designed and synthesized for evaluation as
selective COX-2 inhibitors in vitro and were investigated in vivo as anti-inflammatory and …

Concerted regulation of OPG/RANKL/NF‑κB/MMP-13 trajectories contribute to ameliorative capability of prodigiosin and/or low dose γ-radiation against adjuvant …

MK Abdel-Rafei, NM Thabet, MM Amin - International …, 2022 - Elsevier
Background Prodigiosin (PDG) is a microbial red dye with antioxidant and anti-inflammatory
properties, although its effect on rheumatoid arthritis (RA) remains uncertain. Also, multiple …