The importance of ongoing international surveillance for Creutzfeldt–Jakob disease
N Watson, JP Brandel, A Green, P Hermann… - Nature Reviews …, 2021 - nature.com
Creutzfeldt–Jakob disease (CJD) is a rapidly progressive, fatal and transmissible
neurodegenerative disease associated with the accumulation of misfolded prion protein in …
neurodegenerative disease associated with the accumulation of misfolded prion protein in …
Evidence for zoonotic potential of ovine scrapie prions
Abstract Although Bovine Spongiform Encephalopathy (BSE) is the cause of variant
Creutzfeldt Jakob disease (vCJD) in humans, the zoonotic potential of scrapie prions …
Creutzfeldt Jakob disease (vCJD) in humans, the zoonotic potential of scrapie prions …
Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice
D Padilla, V Béringue, JC Espinosa… - PLoS …, 2011 - journals.plos.org
A new variant of Creutzfeldt Jacob Disease (vCJD) was identified in humans and linked to
the consumption of Bovine Spongiform Encephalopathy (BSE)-infected meat products …
the consumption of Bovine Spongiform Encephalopathy (BSE)-infected meat products …
Atypical/Nor98 scrapie infectivity in sheep peripheral tissues
O Andreoletti, L Orge, SL Benestad, V Beringue… - PLoS …, 2011 - journals.plos.org
Atypical/Nor98 scrapie was first identified in 1998 in Norway. It is now considered as a
worldwide disease of small ruminants and currently represents a significant part of the …
worldwide disease of small ruminants and currently represents a significant part of the …
Preclinical detection of variant CJD and BSE prions in blood
C Lacroux, E Comoy, M Moudjou… - PLoS …, 2014 - journals.plos.org
The emergence of variant Creutzfeldt Jakob Disease (vCJD) is considered a likely
consequence of human dietary exposure to Bovine Spongiform Encephalopathy (BSE) …
consequence of human dietary exposure to Bovine Spongiform Encephalopathy (BSE) …
Insight from animals resistant to prion diseases: Deciphering the genotype–morphotype–phenotype code for the prion protein
Prion diseases are a group of neurodegenerative diseases endemic in humans and several
ruminants caused by the misfolding of native prion protein (PrP) into pathological …
ruminants caused by the misfolding of native prion protein (PrP) into pathological …
Evidence for preexisting prion substrain diversity in a biologically cloned prion strain
T Gunnels, RA Shikiya, TC York, AJ Block… - PLoS …, 2023 - journals.plos.org
Prion diseases are a group of inevitably fatal neurodegenerative disorders affecting
numerous mammalian species, including Sapiens. Prions are composed of PrPSc, the …
numerous mammalian species, including Sapiens. Prions are composed of PrPSc, the …
Chronic wasting disease (CWD) in cervids
EFSA Panel on Biological Hazards (BIOHAZ)… - EFSA …, 2017 - Wiley Online Library
Abstract In April and May of 2016, Norway confirmed two cases of chronic wasting disease
(CWD) in a wild reindeer and a wild moose, respectively. In the light of this emerging issue …
(CWD) in a wild reindeer and a wild moose, respectively. In the light of this emerging issue …
Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie
B Marín, A Otero, S Lugan, JC Espinosa… - Scientific reports, 2021 - nature.com
Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-
BSE) agent following experimental inoculation, and PrPSc accumulation was detected in …
BSE) agent following experimental inoculation, and PrPSc accumulation was detected in …
Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein
Unlike other species, prion disease has never been described in dogs even though they
were similarly exposed to the bovine spongiform encephalopathy (BSE) agent. This …
were similarly exposed to the bovine spongiform encephalopathy (BSE) agent. This …