BACKGROUND Human reproduction depends on an intact hypothalamic–pituitary–gonadal
(HPG) axis. Hypothalamic gonadotrophin-releasing hormone (GnRH) has been recognized …

GnRH and its analogs are used extensively for the treatment of hormone-dependent
diseases and assisted reproductive techniques. They also have potential as novel …

GnRH is the pivotal hypothalamic hormone regulating reproduction. Over 20 forms of the
decapeptide have been identified in which the NH2-and COOH-terminal sequences, which …

Objective: To investigate the expression and function of GnRH and GnRH receptor (GnRHR)
subtypes at the maternal-fetal interface. Design: In vitro experiments using freshly isolated …

Pulsatile gonadotropin-releasing hormone (GnRH) stimulates the pituitary secretion of both
luteinising hormone (LH) and follicle-stimulating hormone (FSH) and thus controls the …

The neuropeptide gonadotropin‐releasing hormone (GnRH) has a central role in the neural
control of vertebrate reproduction. This review describes an overview of what is currently …

In human beings, two forms of GnRH, termed GnRH-I and GnRH-II, encoded by separate
genes have been identified. Although these hormones share comparable cDNA and …

About 50years after Harris's first demonstration of its existence, GnRH has strongly
stimulated the interest and imagination of scientists, resulting in a high number of studies in …

Hypothalamic gonadotrophin-releasing hormone (GnRH I), which is of a variable structure in
vertebrates, is the central regulator of the reproductive system through its stimulation of …

In several human malignant tumors of the urogenital tract, including cancers of the
endometrium, ovary, urinary bladder, and prostate, it has been possible to identify …