One of the challenges posed by current antibacterial therapy is that the expanded and
massive use of antibiotics endows bacteria with the ability to resist almost all kinds of …

Antibiotics have been used as essential therapeutics for nearly 100 years and, increasingly,
as a preventive agent in the agricultural and animal industry. Continuous use and misuse of …

Biomedical devices are essential for patient diagnosis and treatment; however, when blood
comes in contact with foreign surfaces or homeostasis is disrupted, complications including …

Many serious infections result from persistent microbial biofilms that do not respond to
conventional antibiotic therapy. Various therapeutic approaches have been developed and …

Microbes form surface-adherent community structures called biofilms and these biofilms play
a critical role in infection. Biofilms impart antibiotic resistance and sometimes become …

Abstract The emergence of Multi-Drug-Resistant (MDR) organisms has become a major
worldwide clinical problem. The extensive and routine use of the first-line antibiotics to …

This review provides a perspective on porous silicon (pSi)–based nanomaterials including
nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy …

Metal-assisted chemical etching (MACE) affords porous silicon nanostructures control over
size, shape, and porosity in a single step. Simplicity and flexibility are potential advantages …

While best known for its important signalling functions in human physiology, nitric oxide is
also of considerable therapeutic interest. As such, nanoparticle-based systems which …

The nitric oxide (NO) molecule has gained increasing attention in biological applications to
combat biofilm-associated bacterial infections. However, limited NO loading, relatively short …