Epigenetics of lung cancer: a translational perspective
Á Quintanal-Villalonga, S Molina-Pinelo - Cellular Oncology, 2019 - Springer
Background Lung cancer remains the most common cause of cancer-related death, with a 5-
year survival rate of only 18%. In recent years, the development of targeted pharmacological …
year survival rate of only 18%. In recent years, the development of targeted pharmacological …
Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci
Background The mammalian genome is transcribed into large numbers of long noncoding
RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly …
RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly …
Lineage factors and differentiation states in lung cancer progression
WKC Cheung, DX Nguyen - Oncogene, 2015 - nature.com
Lung cancer encompasses a heterogeneous group of malignancies. Here we discuss how
the remarkable diversity of major lung cancer subtypes is manifested in their transforming …
the remarkable diversity of major lung cancer subtypes is manifested in their transforming …
Identification of prognostic gene biomarkers in non-small cell lung cancer progression by integrated bioinformatics analysis
P Giannos, KS Kechagias, A Gal - Biology, 2021 - mdpi.com
Simple Summary Non-small cell lung cancer (NSCLC) is a major contributor to cancer
related deaths worldwide. The progression of NSCLC is linked to epithelial-mesenchymal …
related deaths worldwide. The progression of NSCLC is linked to epithelial-mesenchymal …
Dual ALK and EGFR inhibition targets a mechanism of acquired resistance to the tyrosine kinase inhibitor crizotinib in ALK rearranged lung cancer
N Yamaguchi, AR Lucena-Araujo, S Nakayama… - Lung cancer, 2014 - Elsevier
Introduction The multitargeted tyrosine kinase inhibitor (TKI) crizotinib is active against ALK
translocated non-small-cell lung cancer (NSCLC); however acquired resistance invariably …
translocated non-small-cell lung cancer (NSCLC); however acquired resistance invariably …
Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma
Background DNA methylation has started a recent revolution in genomics biology by
identifying key biomarkers for multiple cancers, including oral squamous cell carcinoma …
identifying key biomarkers for multiple cancers, including oral squamous cell carcinoma …
A high-concentrate diet provokes inflammatory responses by downregulating Forkhead box protein A2 (FOXA2) through epigenetic modifications in the liver of dairy …
W Xie, Y Xue, H Zhang, Y Wang, M Meng, G Chang… - Gene, 2022 - Elsevier
A high-concentrate diet has been reported to promote an inflammatory response in dairy
cows. The purpose of this study was to clarify the effect of the high-concentrate (HC) diet on …
cows. The purpose of this study was to clarify the effect of the high-concentrate (HC) diet on …
CD44 promotes breast cancer metastasis through AKT-mediated downregulation of nuclear FOXA2
The primary cause of breast cancer mortality is the metastatic invasion of cancerous stem
cells (CSC). Cluster of differentiation 44 (CD44) is a well-known CSC marker in various …
cells (CSC). Cluster of differentiation 44 (CD44) is a well-known CSC marker in various …
FOXD1 expression is associated with poor prognosis in non-small cell lung cancer
Aim: Clinical microarray datasets were analyzed to search for new therapeutic targets and
prognostic markers of non-small cell lung cancer (NSCLC). Materials and Methods …
prognostic markers of non-small cell lung cancer (NSCLC). Materials and Methods …
[HTML][HTML] Melatonin suppresses hepatocellular carcinoma progression via lncRNA-CPS1-IT-mediated HIF-1α inactivation
Melatonin is the primary pineal hormone that relays light/dark cycle information to the
circadian system. It was recently reported to exert intrinsic antitumor activity in various …
circadian system. It was recently reported to exert intrinsic antitumor activity in various …