Arginine, transsulfuration, and folic acid pathway metabolomics in chronic obstructive pulmonary disease: a systematic review and meta-analysis
A Zinellu, AA Mangoni - Cells, 2023 - mdpi.com
There is an increasing interest in biomarkers of nitric oxide dysregulation and oxidative
stress to guide management and identify new therapeutic targets in patients with chronic …
stress to guide management and identify new therapeutic targets in patients with chronic …
[HTML][HTML] Circulating arginine metabolites in Alzheimer's disease and vascular dementia: A systematic review and meta-analysis
Background Alterations in nitric oxide (NO) synthesis have been reported in Alzheimer's
disease and vascular dementia. However, as the measurement of NO in biological samples …
disease and vascular dementia. However, as the measurement of NO in biological samples …
Quantitative Analysis of l-Arginine, Dimethylated Arginine Derivatives, l-Citrulline, and Dimethylamine in Human Serum Using Liquid Chromatography–Mass …
MG Fleszar, J Wiśniewski, M Krzystek-Korpacka… - Chromatographia, 2018 - Springer
Nitric oxide (NO) is a small molecule involved in the regulation of many physiological
processes. It plays a crucial role in the regulation of nervous system, immune and …
processes. It plays a crucial role in the regulation of nervous system, immune and …
[HTML][HTML] Small molecule inhibition of DDAH1 significantly attenuates triple negative breast cancer cell vasculogenic mimicry in vitro
Abstract Dimethylarginine dimethylaminohydrolase 1 (DDAH1) is a key enzyme involved in
the metabolism of the endogenous nitric oxide synthase (NOS) inhibitors asymmetric …
the metabolism of the endogenous nitric oxide synthase (NOS) inhibitors asymmetric …
A diethylpyrocarbonate-based derivatization method for the LC-MS/MS measurement of plasma arginine and its chemically related metabolites and analogs
Background Changes in NO metabolism correlate with cardiovascular risk factors and are
associated with endothelial dysfunction. NO availability is regulated by nitric oxide synthase …
associated with endothelial dysfunction. NO availability is regulated by nitric oxide synthase …
Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics
A Radhakutty, BL Mangelsdorf, SM Drake, A Rowland… - Atherosclerosis, 2017 - Elsevier
Background and aims The effects of low dose prednisolone on circulating markers of
endothelial function, the arginine metabolites asymmetric dimethyl arginine (ADMA), mono …
endothelial function, the arginine metabolites asymmetric dimethyl arginine (ADMA), mono …
A novel mass spectrometry‐based method for simultaneous determination of asymmetric and symmetric dimethylarginine, l‐arginine and l‐citrulline optimized for LC …
J Wiśniewski, MG Fleszar, J Piechowicz… - Biomedical …, 2017 - Wiley Online Library
Nitric oxide (NO) is a regulatory molecule involved in many biological processes. NO is
produced by nitric oxide synthase by conversion of l‐arginine to l‐citrulline. l‐Arginine …
produced by nitric oxide synthase by conversion of l‐arginine to l‐citrulline. l‐Arginine …
Arginine metabolomics in mood disorders
Alterations of nitric oxide (NO) homeostasis have been described in mood disorders.
However, the analytical challenges associated with the direct measurement of NO have …
However, the analytical challenges associated with the direct measurement of NO have …
Arginine analogues incorporating carboxylate bioisosteric functions are micromolar inhibitors of human recombinant DDAH-1
Dimethylarginine dimethylaminohydrolase (DDAH) is a key enzyme involved in the
metabolism of asymmetric dimethylarginine (ADMA) and N-monomethyl arginine (NMMA) …
metabolism of asymmetric dimethylarginine (ADMA) and N-monomethyl arginine (NMMA) …
Metabolomic approach to redox and nitrosative reactions in cardiovascular diseases
M Deidda, A Noto, PP Bassareo… - Frontiers in …, 2018 - frontiersin.org
Metabolomics, also referred to as metabonomics, is one of the most recent innovative
technologies in medicine. It offers a direct functional read-out of phenotypes by the …
technologies in medicine. It offers a direct functional read-out of phenotypes by the …