The recognition that asthma is primarily an inflammatory disorder of the airways associated
with T helper type 2 (TH2) cell-dependent promotion of IgE production and recruitment of …

Asthma is a serious health and socioeconomic issue all over the world, affecting more than
300 million individuals. The disease is considered as an inflammatory disease in the airway …

B and T lymphocytes are the mediators of immunity, but their function is under the control of
dendritic cells. Dendritic cells in the periphery capture and process antigens, express …

Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary
immune responses. DCs capture and transfer information from the outside world to the cells …

Whether epithelial cells play a role in triggering the immune cascade leading to T helper 2
(TH2)-type allergic inflammation is not known. We show here that human thymic stromal …

This review is an account of how pulmonary damage caused by cigarette smoke and other
environmental toxins can incite inflammatory and immunologic reactions that culminate in …

Dendritic cells (DC) migrate into inflamed peripheral tissues where they capture antigens
and, following maturation, to lymph nodes where they stimulate T cells. To gain insight into …

The adoption of the concept that asthma is primarily a disease most frequently associated
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …

The control of damaging inflammation by the mucosal immune system in response to
commensal and harmful ingested bacteria is unknown. Here we show epithelial cells …

Mammals generate a diverse array of antimicrobial proteins, largely represented by
defensins or cathelicidins. The direct in vitro microbicidal activity of antimicrobial proteins …