Since its discovery twenty-five years ago, the fat-derived hormone leptin has provided a
revolutionary framework for studying the physiological role of adipose tissue as an …

Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …

Circulating levels of adiponectin (APN) are reduced in obesity and associated comorbidities,
with inflammation playing an important role in downregulating APN production. In contrast to …

In addition to causing cirrhosis and hepatocellular carcinoma, hepatitis C virus (HCV) is
thought to cause hypolipidemia, hepatic steatosis, insulin resistance, metabolic syndrome …

Abstract The Resistin-Like Molecules (RELM) α, β, and γ and their namesake, resistin, share
structural and sequence homology but exhibit significant diversity in expression and function …

Chronic hepatitis C (CHC) is generally a slowly progressive disease, but some factors
associated with rapid progression have been identified. Steatosis, independently of its …

Chronic liver disease (CLD) is a major health problem worldwide. Non-alcoholic fatty liver
disease (NAFLD), chronic hepatitis C (CHC), chronic hepatitis B (CHB), and alcoholic liver …

Background Studies have revealed that resistin plays a role as an intrahepatic cytokine with
proinflammatory activities. This study investigated the association between serum resistin …

Background Apoptosis inhibitor of macrophage (AIM) and adipocytokines are involved in the
metabolic syndrome, which has been putatively associated with the progression of chronic …

Hepatic fibrosis is a dynamic process whereby the liver responds to conditions of persistent
damage. This leads to deposition of fibrillar extracellular matrix, altered hepatocyte …