We argue that, despite the fact that the field of multiscale modelling and simulation has
enjoyed significant success within the past decade, it still holds many open questions that …

Many important scientific problems are inherently multi scale. This is, for instance, the case
in models in material science or environmental science. A big challenge is to formulate …

We expect that multiscale simulations will be one of the main high performance computing
workloads in the exascale era. We propose multiscale computing patterns as a generic …

We review a methodology to design, implement and execute multi-scale and multi-science
numerical simulations. We identify important ingredients of multi-scale modelling and give a …

Inherently complex problems from many scientific disciplines require a multiscale modeling
approach. Yet its practical contents remain unclear and inconsistent. Moreover, multiscale …

This discussion paper introduces the concept of the Virtual Artery as a multiscale model for
arterial physiology and pathologies at the physics–chemistry–biology (PCB) interface. The …

Cellular Automata (CA) are generally acknowledged to be a powerful way to describe and
model natural phenomena [1–3]. There are even tempting claims that nature itself is one big …

In several disciplines, a multiscale approach is being used to model complex natural
processes yet a principled background to multiscale modeling is not clear. Additionally …

In this work, we propose a new numerical procedure for the simulation of time-dependent
problems based on the coupling between the finite element method (FEM) and the lattice …

UvA-DARE (Digital Academic Repository) Page 1 UvA-DARE is a service provided by the
library of the University of Amsterdam (https://dare.uva.nl) UvA-DARE (Digital Academic …