Health benefits of polyphenols: A concise review

A Rana, M Samtiya, T Dhewa, V Mishra… - Journal of Food …, 2022 - Wiley Online Library
Plants produce polyphenols, which are considered highly essential functional foods in our
diet. They are classified into several groups according to their diverse chemical structures …

Phenolic compounds: Current industrial applications, limitations and future challenges

BR Albuquerque, SA Heleno, MBPP Oliveira… - Food & function, 2021 - pubs.rsc.org
Phenolic compounds are natural bioactive molecules found mainly in plant tissues that have
shown interesting bioactivities, such as antioxidant, antimicrobial, anti-inflammatory, and …

Potential adverse effects of resveratrol: A literature review

A Shaito, AM Posadino, N Younes, H Hasan… - International journal of …, 2020 - mdpi.com
Due to its health benefits, resveratrol (RE) is one of the most researched natural
polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the …

Health benefits of resveratrol: Evidence from clinical studies

AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …

The therapeutic potential of resveratrol: a review of clinical trials

AY Berman, RA Motechin, MY Wiesenfeld… - NPJ precision …, 2017 - nature.com
Resveratrol is a nutraceutical with several therapeutic effects. It has been shown to mimic
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …

Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases

AE Kane, DA Sinclair - Circulation research, 2018 - Am Heart Assoc
The sirtuin family of nicotinamide adenine dinucleotide–dependent deacylases (SIRT1–7)
are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and …

Mitochondrial function as a therapeutic target in heart failure

DA Brown, JB Perry, ME Allen, HN Sabbah… - Nature Reviews …, 2017 - nature.com
Heart failure is a pressing worldwide public-health problem with millions of patients having
worsening heart failure. Despite all the available therapies, the condition carries a very poor …

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

MS Bonkowski, DA Sinclair - Nature reviews Molecular cell biology, 2016 - nature.com
Abstract The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-
dependent deacylases with remarkable abilities to prevent diseases and even reverse …

Antioxidant effects of resveratrol in the cardiovascular system

N Xia, A Daiber, U Förstermann… - British journal of …, 2017 - Wiley Online Library
The antioxidant effects of resveratrol (3, 5, 4'‐trihydroxy‐trans‐stilbene) contribute
substantially to the health benefits of this compound. Resveratrol has been shown to be a …

Effect of resveratrol and pterostilbene on aging and longevity

YR Li, S Li, CC Lin - Biofactors, 2018 - Wiley Online Library
Over the past years, several studies have found that foods rich in polyphenols protect
against age‐related disease, such as atherosclerosis, cardiovascular disease, cancer …