Design, spectroscopic characterization, in silico and in vitro cytotoxic activity assessment of newly synthesized thymol Schiff base derivatives

E Başaran, R Çakmak, D Sahin, S Köprü… - Journal of …, 2024 - Taylor & Francis
Cancer is a global public health problem affecting millions of people every year. New
anticancer drug candidates are needed to overcome the resistance to drugs used in the …

Combined experimental and theoretical analyses on design, synthesis, characterization, and in vitro cytotoxic activity evaluation of some novel imino derivatives …

E Başaran, R Çakmak, S Akkoc, S Kaya - Journal of Molecular Structure, 2022 - Elsevier
In this research, some novel Schiff base derivatives 10–18 were synthesized for the first
time, characterized, and tested for their anticancer activities. Spectroscopic characterization …

Schiff base derivatives based on ampyrone as promising acetylcholinesterase inhibitors: Synthesis, spectral characterization, biological activity, and SwissADME …

E Başaran - Russian Journal of Bioorganic Chemistry, 2023 - Springer
In this research, a series of ampyrone-based Schiff base derivatives bearing the biologically
active an aryl sulfonate moiety (X–XVIII) were successfully synthesized and screened for …

An investigation of the biological applications of sulphonated succinimides: in vivo toxicity to zebrafish larvae as well as antioxidant and antimicrobial potential

M Sivanantham, GC Senadi, C Ragavendran… - New Journal of …, 2024 - pubs.rsc.org
Succinimide is a significant structural motif with numerous biological applications. This
investigation reports the biological activity of iodo-sulphonated succinimide derivatives. We …

Synthesis of Novel N-Acylhydrazones Derived from 3,5-Dinitrobenzohydrazide and Evaluation of Their Anticholinesterase and Antioxidant Activities

R Çakmak, E Çınar, E Başaran, G Tuneğ, S İzgi… - Russian Journal of …, 2024 - Springer
Objective: In this study, it was aimed to determine the antioxidant activities and enzyme
inhibition properties of newly synthesized N-acylhydrazone compounds (IIIa–IIIp) bearing an …

[PDF][PDF] Syntheses of some hydrazones derived from 2-(aryloyloxy) benzaldehydes and 2, 4-dinitrophenylhydrazine and evaluation of their anticholinesterase and …

E Çınar, G Topal - Org. Commun, 2022 - acgpubs.org
In this research, five novel hydrazone derivatives (2a-e) were obtained for the first time,
characterized and investigated for their antioxidant properties, and acetylcholinesterase …

SOME NOVEL SCHIFF BASE DERIVATIVES AS PROMISING CHOLINESTERASE INHIBITORS WITH ANTIOXIDANT ACTIVITY AGAINST ALZHEIMER'S DISEASE …

E Çınar, M Boğa, G Topal, R Çakmak - Middle East Journal of …, 2022 - dergipark.org.tr
In this manuscript, five novel Schiff base derivatives containing a pyrazolone ring and a
sulfonate moiety (6-10) except for 9 were designed, obtained for the first time and …

Synthesis and in vitro human carbonic anhydrase I and II inhibition properties of some novel hydrazone compounds containing an aryl sulfonate moiety

R Çakmak - Erzincan University Journal of Science and Technology, 2020 - dergipark.org.tr
The aim of this research was to evaluate the enzyme inhibitory potential of some new
hydrazone derivatives bearing an aryl sulfonate moiety against the human carbonic …