Hypoparathyroidism

M Mannstadt, JP Bilezikian, RV Thakker… - Nature Reviews …, 2017 - nature.com
Hypoparathyroidism is a disease characterized by inadequately low circulating
concentrations of parathyroid hormone (PTH) resulting in low calcium levels and increased …

Genetic, environmental, and epigenetic factors involved in CAKUT

N Nicolaou, KY Renkema, EMHF Bongers… - Nature Reviews …, 2015 - nature.com
Congenital anomalies of the kidney and urinary tract (CAKUT) refer to a spectrum of
structural renal malformations and are the leading cause of end-stage renal disease in …

Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target‐organ involvement, treatment, and challenges for future research

JP Bilezikian, A Khan, JT Potts Jr… - Journal of Bone and …, 2011 - academic.oup.com
Recent advances in understanding the epidemiology, genetics, diagnosis, clinical
presentations, skeletal involvement, and therapeutic approaches to hypoparathyroidism led …

Hypoparathyroidism

D Shoback - New England Journal of Medicine, 2008 - Mass Medical Soc
A 58-year-old man is found on laboratory testing to have a serum calcium level of 6.0 mg per
deciliter (normal range, 8.5 to 10.5), an albumin level of 3.9 g per deciliter, and a …

The emerging role of GATA transcription factors in development and disease

MHFM Lentjes, HEC Niessen, Y Akiyama… - Expert reviews in …, 2016 - cambridge.org
The GATA family of transcription factors consists of six proteins (GATA1-6) which are
involved in a variety of physiological and pathological processes. GATA1/2/3 are required …

[HTML][HTML] GATA-3 function in innate and adaptive immunity

I Tindemans, N Serafini, JP Di Santo, RW Hendriks - Immunity, 2014 - cell.com
The zinc-finger transcription factor GATA-3 has received much attention as a master
regulator of T helper 2 (Th2) cell differentiation, during which it controls interleukin-4 (IL-4) …

Patterned cell and matrix dynamics in branching morphogenesis

S Wang, R Sekiguchi, WP Daley, KM Yamada - Journal of Cell Biology, 2017 - rupress.org
Many embryonic organs undergo branching morphogenesis to maximize their functional
epithelial surface area. Branching morphogenesis requires the coordinated interplay of …

Th1/Th2 cell's function in immune system

Y Zhang, Y Zhang, W Gu, L He, B Sun - T helper cell differentiation and …, 2014 - Springer
CD4+ T helper cells regulate appropriate cellular and humoral immune responses to a wide
range of pathogens and get involved in many diseases progress. The balance of the earliest …

Hypoparathyroidism

JP Bilezikian - The Journal of Clinical Endocrinology & …, 2020 - academic.oup.com
Background Hypoparathyroidism is a rare endocrine disorder characterized by
hypocalcemia and low or undetectable levels of parathyroid hormone. Methods This review …

[HTML][HTML] Prioritization and burden analysis of rare variants in 208 candidate genes suggest they do not play a major role in CAKUT

N Nicolaou, SL Pulit, IJ Nijman, GR Monroe… - Kidney international, 2016 - Elsevier
The leading cause of end-stage renal disease in children is attributed to congenital
anomalies of the kidney and urinary tract (CAKUT). Familial clustering and mouse models …