Interest in the chemistry of ferrocene remains intense, largely due to applications within
catalysis. New synthetic routes to unsymmetrical ferrocene ligands have provided another …

The right choice of a ligand for a metal-catalyzed homogeneous reaction can be as critical
as the choice of the metal itself. In general, ligand design is somewhat like a fine art …

Atropisomeric (hetero) biaryls are motifs with increasing significance in ligands, natural
products, and biologically active molecules. The straightforward construction of the …

A next-generation total synthesis of vancomycin aglycon is detailed that was achieved in 17
steps (longest linear sequence, LLS) from the constituent amino acid subunits with …

Kinetic, spectroscopic, crystallographic, and computational studies probing a Pd-catalyzed C–
H arylation reaction reveal that mono-oxidation of the bis-phosphine ligand is critical for the …

We have shown that Me-DuPHOS monoxide (BozPHOS) is a very effective ligand in the
copper-catalyzed addition of dialkylzinc to N-phosphinoylimines providing access to α-chiral …

A novel catalytic system based on copper (I) and chiral bis (phosphine) dioxides is
described. This allows the arylation of silyl enol ethers to access enolizable α-arylated …

The conversion of aryl halides to primary arylamines with a convenient and inexpensive
source of ammonia has been a long-standing synthetic challenge. Aqueous ammonia would …

The hemilabile ligand Me-DuPHOS (O) 2 has proven to be a successful ligand for the
copper-catalyzed addition of diethylzinc to N-phosphinoylimines. The corresponding α-chiral …

Direct dehydrogenative silylation of pyridyl and iminyl substrates with triethylsilane was
achieved using (L) Ir (cod)(X)(1)(L= a perimidine-based carbene ligand, X= OAc and …