There is increasing interest in the use of edited proton magnetic resonance spectroscopy for
the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a …

Proton NMR chemical shift and J‐coupling values are presented for 35 metabolites that can
be detected by in vivo or in vitro NMR studies of mammalian brain. Measurements were …

Glutamate, a major neurotransmitter in the brain, shows a pH-and concentration-dependent
chemical exchange saturation transfer effect (GluCEST) between its amine group and bulk …

Magnetic resonance (MR; synonymous with NMR= nuclear magnetic resonance) is a
universal physical technique best known for non‐invasive detection and anatomical …

Abstract A two‐dimensional (2D) chemical shift correlated MR spectroscopic (COSY)
sequence integrated into a new volume localization technique (90°–180°–90°) is proposed …

BACKGROUND: At excitatory synapses, glutamate released from neurons is taken up by
glial cells and converted to glutamine, which is cycled back to neurons. Alterations in this …

Patients with task‐specific dystonia (writer's cramp) have impaired cortical inhibition likely
arising from striatal dysfunction. However, the levels of the inhibitory neurotransmitter …

A two‐dimensional fitting procedure is introduced, capable of extracting the full amount of
information from 2D J‐resolved magnetic resonance spectroscopic data. The fitting …

The stiff-person syndrome, a rare and disabling disorder, is characterized by muscle rigidity
and episodic spasms that involve axial and limb musculature. Continuous contraction of …

Recovery of function after acute injury to the central nervous system may be controlled by
the availability of γ‐aminobutyric acid (GABA), the main inhibitory neurotransmitter in the …