Rodent models in neuroscience research: is it a rat race?
B Ellenbroek, J Youn - Disease models & mechanisms, 2016 - journals.biologists.com
Rodents (especially Mus musculus and Rattus norvegicus) have been the most widely used
models in biomedical research for many years. A notable shift has taken place over the last …
models in biomedical research for many years. A notable shift has taken place over the last …
Do different types of stress differentially alter behavioural and neurobiological outcomes associated with depression in rodent models? A systematic review
A Du Preez, J Eum, I Eiben, P Eiben… - Frontiers in …, 2021 - Elsevier
Cataloguing the effects of different types of stress on behaviour and physiology in rodent
models has not been comprehensively attempted. Here, we systematically review whether …
models has not been comprehensively attempted. Here, we systematically review whether …
High-yield methods for accurate two-alternative visual psychophysics in head-fixed mice
Research in neuroscience increasingly relies on the mouse, a mammalian species that
affords unparalleled genetic tractability and brain atlases. Here, we introduce high-yield …
affords unparalleled genetic tractability and brain atlases. Here, we introduce high-yield …
An accumulation-of-evidence task using visual pulses for mice navigating in virtual reality
The gradual accumulation of sensory evidence is a crucial component of perceptual
decision making, but its neural mechanisms are still poorly understood. Given the wide …
decision making, but its neural mechanisms are still poorly understood. Given the wide …
Designing animal-friendly behavioral tests for neuroscience research: the importance of an ethological approach
Behavioral tests have three key elements:(1) a motivating factor (what motivates the animal
in the test);(2) an observable behavior (which behaviors we may expect the animal exhibits …
in the test);(2) an observable behavior (which behaviors we may expect the animal exhibits …
Sensory-to-category transformation via dynamic reorganization of ensemble structures in mouse auditory cortex
The ability to group physical stimuli into behaviorally relevant categories is fundamental to
perception and cognition. Despite a large body of work on stimulus categorization at the …
perception and cognition. Despite a large body of work on stimulus categorization at the …
Novelty detection in an auditory oddball task on freely moving rats
The relative importance or saliency of sensory inputs depend on the animal's environmental
context and the behavioural responses to these same inputs can vary over time. Here we …
context and the behavioural responses to these same inputs can vary over time. Here we …
Magnetic eye tracking in mice
HL Payne, JL Raymond - elife, 2017 - elifesciences.org
Eye movements provide insights about a wide range of brain functions, from sensorimotor
integration to cognition; hence, the measurement of eye movements is an important tool in …
integration to cognition; hence, the measurement of eye movements is an important tool in …
Stable representation of sounds in the posterior striatum during flexible auditory decisions
L Guo, WI Walker, ND Ponvert, PL Penix… - Nature …, 2018 - nature.com
The neuronal pathways that link sounds to rewarded actions remain elusive. For instance, it
is unclear whether neurons in the posterior tail of the dorsal striatum (which receive direct …
is unclear whether neurons in the posterior tail of the dorsal striatum (which receive direct …
[HTML][HTML] From innate to instructed: A new look at perceptual decision-making
LT Oesch, MB Ryan, AK Churchland - Current Opinion in Neurobiology, 2024 - Elsevier
Understanding how subjects perceive sensory stimuli in their environment and use this
information to guide appropriate actions is a major challenge in neuroscience. To study …
information to guide appropriate actions is a major challenge in neuroscience. To study …