The growth hormone receptor (GHR), although most well known for regulating growth, has
many other important biological functions including regulating metabolism and controlling …

Consistent evidence associates IGF-1 deficiency and metabolic syndrome. In this review, we
will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its …

CD36/FAT (fatty acid translocase) is associated with human and murine nonalcoholic fatty
liver disease, but it has been unclear whether it is simply a marker or whether it directly …

Diabetes and cancer are two heterogeneous, multifactorial, severe, and chronic diseases.
Because of their frequency, reciprocal influences–even minor influences–may have a major …

Patients with obesity have a high prevalence of nonalcoholic fatty liver disease (NAFLD),
representing a spectrum of simple steatosis to nonalcoholic steatohepatitis (NASH), without …

IGF-I is expressed in virtually every tissue of the body, but with much higher expression in
the liver than in any other tissue. Studies using mice with liver-specific IGF-I knockout have …

Growth hormone (GH) is a key determinant of postnatal growth and plays an important role
in the control of metabolism and body composition. Surprisingly, deficiency in GH signaling …

This review will summarize the metabolic effects of growth hormone (GH) on the adipose
tissue, liver, and skeletal muscle with focus on lipid and carbohydrate metabolism. The …

Despite increased use of the hyperinsulinemic-euglycemic clamp to study insulin action in
mice, the effects of experimental parameters on the results obtained have not been …

Anabolic-androgenic steroids (AAS) and other hormones such as growth hormone (GH) and
insulin-like growth factor-1 (IGF-1) have been shown to increase muscle mass in patients …