Intestinal mucosal barrier function in health and disease
JR Turner - Nature reviews immunology, 2009 - nature.com
Mucosal surfaces are lined by epithelial cells. These cells establish a barrier between
sometimes hostile external environments and the internal milieu. However, mucosae are …
sometimes hostile external environments and the internal milieu. However, mucosae are …
CD8+ T Lymphocytes: Crucial Players in Sjögren's Syndrome
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease associated with
damage to multiple organs and glands. The most common clinical manifestations are dry …
damage to multiple organs and glands. The most common clinical manifestations are dry …
A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK …
J Miyamoto, T Mizukure, SB Park, S Kishino… - Journal of Biological …, 2015 - ASBMB
Gut microbial metabolites of polyunsaturated fatty acids have attracted much attention
because of their various physiological properties. Dysfunction of tight junction (TJ) in the …
because of their various physiological properties. Dysfunction of tight junction (TJ) in the …
HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity
BJ Saeedi, DJ Kao, DA Kitzenberg… - Molecular biology of …, 2015 - Am Soc Cell Biol
Intestinal epithelial cells (IECs) are exposed to profound fluctuations in oxygen tension and
have evolved adaptive transcriptional responses to a low-oxygen environment. These …
have evolved adaptive transcriptional responses to a low-oxygen environment. These …
Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases
JC Hall, L Casciola-Rosen, AE Berger… - Proceedings of the …, 2012 - National Acad Sciences
Elucidating the molecular pathways active in pathologic tissues has important implications
for defining disease subsets, selecting therapy, and monitoring disease activity. The …
for defining disease subsets, selecting therapy, and monitoring disease activity. The …
Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins
CT Capaldo, AE Farkas, RS Hilgarth… - Molecular biology of …, 2014 - Am Soc Cell Biol
Tight junctions (TJs) are dynamic, multiprotein intercellular adhesive contacts that provide a
vital barrier function in epithelial tissues. TJs are remodeled during physiological …
vital barrier function in epithelial tissues. TJs are remodeled during physiological …
Disruption of tight junction structure in salivary glands from Sjögren's syndrome patients is linked to proinflammatory cytokine exposure
P Ewert, S Aguilera, C Alliende, YJ Kwon… - Arthritis & …, 2010 - Wiley Online Library
Objective Disorganization of acinar cell apical microvilli and the presence of stromal
collagen in the acinar lumen suggest that the labial salivary gland (LSG) barrier function is …
collagen in the acinar lumen suggest that the labial salivary gland (LSG) barrier function is …
Aquaporin gene therapy corrects Sjögren's syndrome phenotype in mice
Z Lai, H Yin, J Cabrera-Pérez… - Proceedings of the …, 2016 - National Acad Sciences
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that is estimated to
affect 35 million people worldwide. Currently, no effective treatments exist for Sjögren's …
affect 35 million people worldwide. Currently, no effective treatments exist for Sjögren's …
Effect of dietary phosphorus deficiency on the growth, immune function and structural integrity of head kidney, spleen and skin in young grass carp …
K Chen, WD Jiang, P Wu, Y Liu, SY Kuang… - Fish & Shellfish …, 2017 - Elsevier
This study evaluates the effects of dietary phosphorus on the growth, immune function and
structural integrity (head kidney, spleen and skin) of young grass carp (Ctenopharyngodon …
structural integrity (head kidney, spleen and skin) of young grass carp (Ctenopharyngodon …
[PDF][PDF] Salivary cytokine profiles in primary Sjögren's syndrome differ from those in non-Sjögren sicca in terms of TNF-α levels and Th-1/Th-2 ratios
EH Kang, YJ Lee, JY Hyon, PY Yun… - Clinical and …, 2011 - clinexprheumatol.org
CLIN EXP RHEUM 29/6 FINAL Page 1 Clinical and Experimental Rheumatology 2011; 29:
970-976. Salivary cytokine profiles in primary Sjögren’s syndrome differ from those in non-Sjögren …
970-976. Salivary cytokine profiles in primary Sjögren’s syndrome differ from those in non-Sjögren …