Multiple genetic and environmental factors have been associated with an increased risk for
rheumatoid arthritis (RA). Of these, the strongest associations have been seen with female …

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting 3% of the
world's population, and approximately one-third of patients with psoriasis will eventually …

Gut microbial dysbiosis is associated with the development of autoimmune disease, but the
mechanisms by which microbial dysbiosis affects the transition from asymptomatic …

Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with
poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral …

We carried out metagenomic shotgun sequencing and a metagenome-wide association
study (MGWAS) of fecal, dental and salivary samples from a cohort of individuals with …

Characterization and understanding of gut microbiota has recently increased representing a
wide research field, especially in autoimmune diseases. Gut microbiota is the major source …

Metagenome-wide association studies (MWAS) have enabled the high-resolution
investigation of associations between the human microbiome and several complex …

Gut microbiota profoundly affect gut and systemic diseases, but the mechanism whereby
microbiota affect systemic diseases is unclear. It is not known whether specific microbiota …

Rheumatoid arthritis (RA), a common autoimmune disease, is characterized by a highly
coordinated inflammatory response that involves innate and adaptive immunity. One of the …

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic joint
inflammation which ultimately leads to severe disability and premature mortality. It has a …