The glymphatic system: Current understanding and modeling
We review theoretical and numerical models of the glymphatic system, which circulates
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …
Cerebrospinal fluid flow
Circulation of cerebrospinal fluid and interstitial fluid around the central nervous system and
through the brain transports not only those water-like fluids but also any solutes they carry …
through the brain transports not only those water-like fluids but also any solutes they carry …
Current understanding of the anatomy, physiology, and magnetic resonance imaging of neurofluids: update from the 2022 “ISMRM Imaging Neurofluids Study group” …
Neurofluids is a term introduced to define all fluids in the brain and spine such as blood,
cerebrospinal fluid, and interstitial fluid. Neuroscientists in the past millennium have steadily …
cerebrospinal fluid, and interstitial fluid. Neuroscientists in the past millennium have steadily …
The glymphatic system in humans: investigations with magnetic resonance imaging
The concept of the glymphatic system was proposed more than a decade ago as a
mechanism for interstitial fluid flow and waste removal in the central nervous system. The …
mechanism for interstitial fluid flow and waste removal in the central nervous system. The …
[HTML][HTML] Novel developments in non-contrast enhanced MRI of the perivascular clearance system: What are the possibilities for Alzheimer's disease research?
MM van der Thiel, WH Backes, IHGB Ramakers… - Neuroscience & …, 2023 - Elsevier
The cerebral waste clearance system (ie, glymphatic or intramural periarterial drainage)
works through a network of perivascular spaces (PVS). Dysfunction of this system likely …
works through a network of perivascular spaces (PVS). Dysfunction of this system likely …
Physiology of glymphatic solute transport and waste clearance from the brain
L Zhao, A Tannenbaum, ENTP Bakker… - …, 2022 - journals.physiology.org
This review focuses on the physiology of glymphatic solute transport and waste clearance,
using evidence from experimental animal models as well as from human studies. Specific …
using evidence from experimental animal models as well as from human studies. Specific …
Diffusion magnetic resonance imaging of cerebrospinal fluid dynamics: Current techniques and future advancements
Cerebrospinal fluid (CSF) plays a critical role in metabolic waste clearance from the brain,
requiring its circulation throughout various brain pathways, including the ventricular system …
requiring its circulation throughout various brain pathways, including the ventricular system …
Cerebrospinal fluid turnover as a driver of brain clearance
NG Smets, GJ Strijkers, V Vinje… - NMR in …, 2024 - Wiley Online Library
Cerebrospinal fluid (CSF) has historically been considered to function as a sink for brain‐
derived waste disposal. Recent work suggested that CSF interacts even more intensely with …
derived waste disposal. Recent work suggested that CSF interacts even more intensely with …
[HTML][HTML] Age-related decline of intrinsic cerebrospinal fluid outflow in healthy humans detected with non-contrast spin-labeling MR imaging
Purpose Clearance of cerebrospinal fluid (CSF) is important for the removal of toxins from
the brain, with implications for neurodegenerative diseases. Imaging evaluation of CSF …
the brain, with implications for neurodegenerative diseases. Imaging evaluation of CSF …
[HTML][HTML] Choroid plexus tissue perfusion and blood to CSF barrier function in rats measured with continuous arterial spin labeling
The choroid plexus (ChP) of the cerebral ventricles is a source of cerebrospinal fluid (CSF)
production and also plays a key role in immune surveillance at the level of blood-to-CSF …
production and also plays a key role in immune surveillance at the level of blood-to-CSF …