Metallo-β-lactamases: structure, function, epidemiology, treatment options, and the development pipeline
SE Boyd, DM Livermore, DC Hooper… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Modern medicine is threatened by the global rise of antibiotic resistance, especially among
Gram-negative bacteria. Metallo-β-lactamase (MBL) enzymes are a particular concern and …
Gram-negative bacteria. Metallo-β-lactamase (MBL) enzymes are a particular concern and …
Mechanisms of antibiotic resistance in important gram-positive and gram-negative pathogens and novel antibiotic solutions
Multidrug-resistant bacteria have on overwhelming impact on human health, as they cause
over 670,000 infections and 33,000 deaths annually in the European Union alone. Of these …
over 670,000 infections and 33,000 deaths annually in the European Union alone. Of these …
OXA-48-like carbapenemases producing Enterobacteriaceae in different niches
A Mairi, A Pantel, A Sotto, JP Lavigne… - European Journal of …, 2018 - Springer
The emergence of carbapenem-resistant enterobacterial species poses a serious threat to
public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are …
public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are …
Bacterial profile, their antibiotic susceptibility pattern, and associated factors of urinary tract infections in children at Hiwot Fana Specialized University Hospital …
Background Urinary tract infections (UTIs) are common pediatric infections and contribute to
high morbidity and mortality. At present, the antimicrobial resistance emergency has …
high morbidity and mortality. At present, the antimicrobial resistance emergency has …
An overview of antimicrobial resistance in Saudi Arabia (2013–2023) and the need for national surveillance
AK Thabit, AY Alabbasi, FS Alnezary, IA Almasoudi - Microorganisms, 2023 - mdpi.com
Antimicrobial resistance (AMR) is a well-recognized global threat. The World Health
Organization (WHO) issued a report ranking the critical types of bacterial resistance that …
Organization (WHO) issued a report ranking the critical types of bacterial resistance that …
Antimicrobial Resistance and Prevalence of Extended Spectrum β-Lactamase-Producing Escherichia coli from Dogs and Cats in Northeastern China from 2012 to …
Y Zhou, X Ji, B Liang, B Jiang, Y Li, T Yuan, L Zhu… - Antibiotics, 2022 - mdpi.com
(1) Background: there has been a growing concern about pet-spread bacterial zoonosis in
recent years. This study aimed to investigate the trend in drug-resistance of canine …
recent years. This study aimed to investigate the trend in drug-resistance of canine …
Co-Existence of Certain ESBLs, MBLs and Plasmid Mediated Quinolone Resistance Genes among MDR E. coli Isolated from Different Clinical Specimens in Egypt
The emergence of multi-drug resistant (MDR) strains and even pan drug resistant (PDR)
strains is alarming. In this study, we studied the resistance pattern of E. coli pathogens …
strains is alarming. In this study, we studied the resistance pattern of E. coli pathogens …
Molecular Characterization of Antibiotic Resistance Determinants in Klebsiella pneumoniae Isolates Recovered from Hospital Effluents in the Eastern Cape Province …
JU Okafor, UU Nwodo - Antibiotics, 2023 - mdpi.com
Klebsiella pneumoniae (K. pneumoniae) is an opportunistic bacteria responsible for many
nosocomial and community-acquired infections. The emergence and spread of antibiotic …
nosocomial and community-acquired infections. The emergence and spread of antibiotic …
The Molecular Characterization of Nosocomial Carbapenem-Resistant Klebsiella pneumoniae Co-Harboring blaNDM and blaOXA-48 in Jeddah
W Alhazmi, A Al-Jabri, I Al-Zahrani - Microbiology Research, 2022 - mdpi.com
Carbapenem-resistant Klebsiella pneumoniae (CRKP)-associated infections have become
a major concern and life-threatening worldwide. Understanding the epidemiology of CRKP …
a major concern and life-threatening worldwide. Understanding the epidemiology of CRKP …
[HTML][HTML] Molecular characterization, antimicrobial resistance and clinico-bioinformatics approaches to address the problem of extended-spectrum β-lactamase …
The goal of this study was to genotypically characterize extended-spectrum β-lactamase-
producing Escherichia coli isolates from the western region of Saudi Arabia and to identify …
producing Escherichia coli isolates from the western region of Saudi Arabia and to identify …