Controversies and evolving new mechanisms in subarachnoid hemorrhage

S Chen, H Feng, P Sherchan, D Klebe, G Zhao… - Progress in …, 2014 - Elsevier
Despite decades of study, subarachnoid hemorrhage (SAH) continues to be a serious and
significant health problem in the United States and worldwide. The mechanisms contributing …

The pathophysiology and treatment of delayed cerebral ischaemia following subarachnoid haemorrhage

KP Budohoski, M Guilfoyle, A Helmy… - Journal of Neurology …, 2014 - jnnp.bmj.com
Cerebral vasospasm has traditionally been regarded as an important cause of delayed
cerebral ischaemia (DCI) which occurs after aneurysmal subarachnoid haemorrhage, and …

Cerebral vasospasm: a review

JM Findlay, J Nisar, T Darsaut - Canadian Journal of Neurological …, 2016 - cambridge.org
Cerebral vasospasm is a prolonged but reversible narrowing of cerebral arteries beginning
days after subarachnoid hemorrhage. Progression to cerebral ischemia is tied mostly to …

Delayed cerebral ischemia after subarachnoid hemorrhage

A Ikram, MA Javaid, S Ortega-Gutierrez, M Selim… - Journal of stroke and …, 2021 - Elsevier
Delayed cerebral ischemia (DCI) is the most feared complication of aneurysmal
subarachnoid hemorrhage (aSAH). It increases the mortality and morbidity associated with …

[HTML][HTML] Neuroprotective role of the Nrf2 pathway in subarachnoid haemorrhage and its therapeutic potential

A Zolnourian, I Galea, D Bulters - Oxidative medicine and cellular …, 2019 - hindawi.com
The mechanisms underlying poor outcome following subarachnoid haemorrhage (SAH) are
complex and multifactorial. They include early brain injury, spreading depolarisation …

Early prediction of delayed cerebral ischemia in subarachnoid hemorrhage based on quantitative EEG: a prospective study in adults

S Gollwitzer, T Groemer, S Rampp, M Hagge… - Clinical …, 2015 - Elsevier
Objectives Delayed cerebral infarction (DCI) has a significant impact on mortality and
morbidity of patients with subarachnoid hemorrhage (SAH). The aim of this study was to …

Effect of cilostazol on cerebral vasospasm and outcome in patients with aneurysmal subarachnoid hemorrhage: a randomized, double-blind, placebo-controlled trial

N Matsuda, M Naraoka, H Ohkuma… - Cerebrovascular …, 2016 - karger.com
Background: Several clinical studies have indicated the efficacy of cilostazol, a selective
inhibitor of phosphodiesterase 3, in preventing cerebral vasospasm after aneurysmal …

Aneurysmal subarachnoid hemorrhage: pathobiology, current treatment and future directions

JC Serrone, H Maekawa, M Tjahjadi… - Expert review of …, 2015 - Taylor & Francis
Aneurysmal subarachnoid hemorrhage is the most devastating form of stroke. Many
pathological mechanisms ensue after cerebral aneurysm rupture, including hydrocephalus …

Pathophysiologic differences in cerebral autoregulation after subarachnoid hemorrhage

GA Santos, N Petersen, AA Zamani, R Du, S LaRose… - Neurology, 2016 - AAN Enterprises
Objective: To understand the physiologic basis of impaired cerebral autoregulation in
subarachnoid hemorrhage (SAH) and its relationship to neurologic outcomes. Methods: The …

[HTML][HTML] Diagnosis of delayed cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage and triggers for intervention

A Abdulazim, M Heilig, G Rinkel, N Etminan - Neurocritical Care, 2023 - Springer
Introduction Delayed cerebral ischemia (DCI) is a major determinant for poor neurological
outcome after aneurysmal subarachnoid hemorrhage (aSAH). Detection and treatment of …