Sepsis is a persistent systemic inflammatory condition involving multiple organ failures
resulting from a dysregulated immune response to infection, and one of the hallmarks of …

Sepsis is defined as “a life-threatening organ dysfunction caused by a host's dysfunctional
response to infection”. Although the treatment of sepsis has developed rapidly in the past …

Background Effective removal of pathogenic bacteria is key to improving the prognosis of
sepsis. Polymorphonuclear neutrophils (PMNs) are the most important components of innate …

Neutrophils are the most abundant, short lived, and terminally differentiated leukocytes with
distinct tiers of arsenals to counter pathogens. Neutrophils were traditionally considered …

Sepsis is a life-threatening disorder disease defined as infection-induced dysregulated
immune responses and multiple organ dysfunction. The imbalance between …

Sepsis is characterized by a dysregulated immune response to infections that causes life-
threatening organ dysfunction and even death. When infections occur, bacterial cell wall …

Sepsis-associated encephalopathy (SAE) is commonly complicated by septic conditions,
and is responsible for increased mortality and poor outcomes in septic patients …

A sufficient response of neutrophil granulocytes stimulated by interleukin (IL)-8 is vital during
systemic inflammation, for example, in sepsis or severe trauma. Moreover, IL-8 is clinically …

Following strong activation signals, several types of immune cells reportedly release
chromatin and granular proteins into the extracellular space, forming DNA traps. This …

Sepsis is a dysregulated host response to an infection, characterized by organ failure. The
pathophysiology is complex and incompletely understood, but mitochondria appear to play a …