Carbohydrate-active enzymes (CAZymes) in the gut microbiome

JF Wardman, RK Bains, P Rahfeld… - Nature Reviews …, 2022 - nature.com
The 1013–1014 microorganisms present in the human gut (collectively known as the human
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …

Glycosyltransferases: structures, functions, and mechanisms

LL Lairson, B Henrissat, GJ Davies… - Annu. Rev …, 2008 - annualreviews.org
Glycosyltransferases catalyze glycosidic bond formation using sugar donors containing a
nucleoside phosphate or a lipid phosphate leaving group. Only two structural folds, GT-A …

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Y Qin, AS Havulinna, Y Liu, P Jousilahti, SC Ritchie… - Nature Genetics, 2022 - nature.com
Human genetic variation affects the gut microbiota through a complex combination of
environmental and host factors. Here we characterize genetic variations associated with …

[HTML][HTML] Host genetic regulation of human gut microbial structural variation

DV Zhernakova, D Wang, L Liu, S Andreu-Sánchez… - Nature, 2024 - nature.com
Although the impact of host genetics on gut microbial diversity and the abundance of specific
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …

Genomic insights into the Acidobacteria reveal strategies for their success in terrestrial environments

SA Eichorst, D Trojan, S Roux… - Environmental …, 2018 - Wiley Online Library
Members of the phylum Acidobacteria are abundant and ubiquitous across soils. We
performed a large‐scale comparative genome analysis spanning subdivisions 1, 3, 4, 6, 8 …

Blood groups systems

R Mitra, N Mishra, GP Rath - Indian journal of anaesthesia, 2014 - journals.lww.com
Abstract International Society of Blood Transfusion has recently recognized 33 blood group
systems. Apart from ABO and Rhesus system, many other types of antigens have been …

Oxidoreductive cellulose depolymerization by the enzymes cellobiose dehydrogenase and glycoside hydrolase 61

JA Langston, T Shaghasi, E Abbate, F Xu… - Applied and …, 2011 - Am Soc Microbiol
Several members of the glycoside hydrolase 61 (GH61) family of proteins have recently
been shown to dramatically increase the breakdown of lignocellulosic biomass by microbial …

RIFINs are adhesins implicated in severe Plasmodium falciparum malaria

S Goel, M Palmkvist, K Moll, N Joannin, P Lara… - Nature medicine, 2015 - nature.com
Rosetting is a virulent Plasmodium falciparum phenomenon associated with severe malaria.
Here we demonstrate that P. falciparum–encoded repetitive interspersed families of …

Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs

A Wang, RVP Ribeiro, A Ali, E Brambate… - Science Translational …, 2022 - science.org
Donor organ allocation is dependent on ABO matching, restricting the opportunity for some
patients to receive a life-saving transplant. The enzymes FpGalNAc deacetylase and …

Taxonomic and carbon metabolic diversification of Bathyarchaeia during its coevolution history with early Earth surface environment

J Hou, Y Wang, P Zhu, N Yang, L Liang, T Yu, M Niu… - Science …, 2023 - science.org
Bathyarchaeia, as one of the most abundant microorganisms on Earth, play vital roles in the
global carbon cycle. However, our understanding of their origin, evolution, and ecological …