Advances in the development of antiviral strategies against parvovirus B19

E Manaresi, G Gallinella - Viruses, 2019 - mdpi.com
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …

Recent advances in replication and infection of human parvovirus B19

SS Ganaie, J Qiu - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Parvovirus B19 (B19V) is pathogenic to humans and causes bone marrow failure diseases
and various other inflammatory disorders. B19V infection exhibits high tropism for human …

[HTML][HTML] Lrp1 is a host entry factor for Rift Valley fever virus

SS Ganaie, MM Schwarz, CM McMillen, DA Price… - Cell, 2021 - cell.com
Rift Valley fever virus (RVFV) is a zoonotic pathogen with pandemic potential. RVFV entry is
mediated by the viral glycoprotein (Gn), but host entry factors remain poorly defined. Our …

Identification of AXL as a co-receptor for human parvovirus B19 infection of human erythroid progenitors

K Ning, W Zou, P Xu, F Cheng, EY Zhang… - Science …, 2023 - science.org
Parvovirus B19 (B19V) infects human erythroid progenitor cells (EPCs) and causes several
hematological disorders and fetal hydrops. Amino acid (aa) 5–68 of minor capsid protein …

Integrative transcriptomics analysis of lung epithelial cells and identification of repurposable drug candidates for COVID-19

T Islam, MR Rahman, B Aydin, H Beklen… - European Journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease, more commonly
COVID-19 has emerged as a world health pandemic. There are couples of treatment …

The dynamic interface of viruses with STATs

AR Harrison, GW Moseley - Journal of virology, 2020 - Am Soc Microbiol
Viruses commonly antagonize the antiviral type I interferon response by targeting signal
transducer and activator of transcription 1 (STAT1) and STAT2, key mediators of interferon …

Human parvovirus B19 utilizes cellular DNA replication machinery for viral DNA replication

W Zou, Z Wang, M Xiong, AY Chen, P Xu… - Journal of …, 2018 - Am Soc Microbiol
ABSTRACT Human parvovirus B19 (B19V) infection of human erythroid progenitor cells
(EPCs) induces a DNA damage response and cell cycle arrest at late S phase, which …

For better or worse: crosstalk of parvovirus and host DNA damage response

S Chen, F Liu, A Yang, K Shang - Frontiers in Immunology, 2024 - frontiersin.org
Parvoviruses are a group of non-enveloped DNA viruses that have a broad spectrum of
natural infections, making them important in public health. NS1 is the largest and most …

The clinical use of parvovirus B19 assays: recent advances

G Gallinella - Expert Review of Molecular Diagnostics, 2018 - Taylor & Francis
ABSTRACT Introduction: Parvovirus B19 (B19V), a single-stranded DNA virus in the family
Parvoviridae, is a human pathogenic virus, characterized by a selective but not exclusive …

High-throughput screening identifies inhibitors for parvovirus B19 infection of human erythroid progenitors

K Ning, A Roy, F Cheng, P Xu, S Kleiboeker… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT Parvovirus B19 (B19V) infection can cause hematological disorders and fetal
hydrops during pregnancy. Currently, no antivirals or vaccines are available for the …