[HTML][HTML] The impact of hypoxia in early pregnancy on placental cells
H Zhao, RJ Wong, DK Stevenson - International journal of molecular …, 2021 - mdpi.com
Oxygen levels in the placental microenvironment throughout gestation are not constant, with
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …
severe hypoxic conditions present during the first trimester. This hypoxic phase overlaps …
Epigenetics and the placenta
ECM Nelissen, APA van Montfoort… - Human reproduction …, 2011 - academic.oup.com
BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …
Unfolding the cascade of SERPINA3: Inflammation to cancer
A Soman, SA Nair - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Abstract SERine Protease INhibitor clade A member 3 (SERPINA3), a member of the
SERine-Protease INhibitor (SERPIN) superfamily, principally works as a protease inhibitor in …
SERine-Protease INhibitor (SERPIN) superfamily, principally works as a protease inhibitor in …
[HTML][HTML] Epigenetic biomarkers in cardiovascular diseases
C Soler-Botija, C Gálvez-Montón… - Frontiers in genetics, 2019 - frontiersin.org
Cardiovascular diseases are the number one cause of death worldwide and greatly impact
quality of life and medical costs. Enormous effort has been made in research to obtain new …
quality of life and medical costs. Enormous effort has been made in research to obtain new …
[HTML][HTML] Role of nitric oxide in placental vascular development and function
BJ Krause, MA Hanson, P Casanello - Placenta, 2011 - Elsevier
Nitric oxide (NO) is one of the most pleiotropic signaling molecules at systemic and cellular
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …
levels, participating in vascular tone regulation, cellular respiration, proliferation, apoptosis …
Immune system disturbances in schizophrenia
Epidemiological, genetic, transcriptome, postmortem, peripheral biomarker, and therapeutic
studies of schizophrenia all point to a dysregulation of both innate and adaptive immune …
studies of schizophrenia all point to a dysregulation of both innate and adaptive immune …
Epigenetic control of fetal gene expression
TM Nafee, WE Farrell, WD Carroll… - … Journal of Obstetrics …, 2008 - Wiley Online Library
Each differentiated cell type has its own epigenetic signature, which reflects its genotype,
developmental history, and environmental influences, and is ultimately reflected in the …
developmental history, and environmental influences, and is ultimately reflected in the …
[HTML][HTML] DNA methylation profiling of human placentas reveals promoter hypomethylation of multiple genes in early-onset preeclampsia
RKC Yuen, MS Penaherrera… - European Journal of …, 2010 - nature.com
Preeclampsia and intrauterine growth restriction (IUGR) are two of the most common
adverse pregnancy outcomes, but their underlying causes are mostly unknown. Although …
adverse pregnancy outcomes, but their underlying causes are mostly unknown. Although …
[HTML][HTML] DNA methylation in the human placenta and fetal growth
O Koukoura, S Sifakis… - Molecular medicine …, 2012 - spandidos-publications.com
Throughout in utero development, the placenta plays a key role in controlling growth and
development. The placenta acts not only as a gatekeeper of nutrient and waste exchange …
development. The placenta acts not only as a gatekeeper of nutrient and waste exchange …
Hypertensive disorders of pregnancy and DNA methylation in newborns: findings from the pregnancy and childhood epigenetics consortium
N Kazmi, GC Sharp, SE Reese, FO Vehmeijer… - …, 2019 - Am Heart Assoc
Hypertensive disorders of pregnancy (HDP) are associated with low birth weight, shorter
gestational age, and increased risk of maternal and offspring cardiovascular diseases later …
gestational age, and increased risk of maternal and offspring cardiovascular diseases later …