Radioactive main group and rare earth metals for imaging and therapy

TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Modern developments in bifunctional chelator design for gallium radiopharmaceuticals

PRWJ Davey, BM Paterson - Molecules, 2022 - mdpi.com
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …

Electrochemical Dehydrogenative Coupling of Alcohols with Hydrogen Phosphoryl Compounds: A Green Protocol for P− O Bond Formation

QY Li, TR Swaroop, C Hou, ZQ Wang… - Advanced Synthesis …, 2019 - Wiley Online Library
This study reports the environment‐friendly electrochemical transformation of structurally
diverse phosphorus compounds and alcohol into phosphonates in the presence of …

Microwave hydrothermal synthesis of gallotannin/carbon nanotube composites for the recovery of gallium ion

Y Xiong, X Cui, M Zhang, Y Wang, Z Lou… - Applied Surface Science, 2020 - Elsevier
Ultrafast and facile microwave hydrothermal approach was applied to synthesize gallotannin
modified carbon nanotube composites (CNT-GT) for effective recovery of Ga (III) from …

A UV-Vis method for investigation of gallium (iii) complexation kinetics with NOTA and TRAP chelators: advantages, limitations and comparison with radiolabelling

V Lebruška, T Dobrovolná, T Gemperle… - Dalton …, 2024 - pubs.rsc.org
An easy and cheap method for measurement of GaIII complexation kinetics was developed.
The method is based on UV-Vis quantification of non-complexed chelators after the addition …

Synthesis and evaluation of new bifunctional chelators with Phosphonic acid arms for Gallium-68 based PET imaging in melanoma

Y Gai, L Sun, X Lan, D Zeng, G Xiang… - Bioconjugate …, 2018 - ACS Publications
Due to the increasing use of generator-produced radiometal Gallium-68 (68Ga) in positron-
emission tomography/computed tomography (PET/CT), reliable bifunctional chelators that …

Chelation in One Fell Swoop: Optimizing Ligands for Smaller Radiometal Ions

N Choudhary… - Inorganic …, 2020 - ACS Publications
[44/47Sc] Sc3+,[68Ga] Ga3+, and [111In] In3+ are the three most attractive trivalent smaller
radiometalnuclides, offering a wide range of distinct properties (emission energies and …

Selective separation of Fe and Ga from Al-containing HNO3 leach liquor using cupferron: Efficiency, mechanism, and regeneration

S Shi, B Ma, H Yang, Y Chen, C Wang - Chemical Engineering Journal, 2024 - Elsevier
Coal gangue and fly ash are typical coal-based solid waste and can be considered as Al
and Ga resources. The HNO 3 leaching technology was proposed by our team for the …

HER3 PET Imaging: 68Ga-Labeled Affibody Molecules Provide Superior HER3 Contrast to 89Zr-Labeled Antibody and Antibody-Fragment-Based Tracers

SS Rinne, CD Leitao, A Abouzayed, A Vorobyeva… - Cancers, 2021 - mdpi.com
Simple Summary HER3 is a known driver for oncogenesis and therapy resistance in solid
cancers. PET imaging could be a useful tool to non-invasively detect and monitor HER3 …

Increase in negative charge of 68Ga/chelator complex reduces unspecific hepatic uptake but does not improve imaging properties of HER3-targeting affibody …

SS Rinne, C Dahlsson Leitao, J Gentry, B Mitran… - Scientific Reports, 2019 - nature.com
Upregulation of the human epidermal growth factor receptor type 3 (HER3) is a common
mechanism to bypass HER-targeted cancer therapy. Affibody-based molecular imaging has …