Viruses are intracellular parasites that use the host cell they infect to produce new infectious
progeny. Distinct steps of the virus life cycle occur in association with the cytoskeleton or …

In this review, we summarize the current knowledge about the membranous replication
factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of …

Many RNA viruses remodel intracellular membranes to generate specialized sites for RNA
replication. How membranes are remodeled and what properties make them conducive for …

The cytoplasmic replication of positive-sense RNA viruses is associated with a dramatic
rearrangement of host cellular membranes. These virus-induced changes result in the …

Plus-strand RNA virus replication occurs in tight association with cytoplasmic host cell
membranes. Both, viral and cellular factors cooperatively generate distinct organelle-like …

Genome replication and assembly of viruses often takes place in specific intracellular
compartments where viral components concentrate, thereby increasing the efficiency of the …

All positive-strand RNA viruses of eukaryotes studied assemble RNA replication complexes
on the surfaces of cytoplasmic membranes. Infection of mammalian cells with poliovirus and …

The replication complexes (RCs) of positive-stranded RNA viruses are intimately associated
with cellular membranes. To investigate membrane alterations and to characterize the RC of …

The endoplasmic reticulum (ER) is the largest intracellular organelle. It forms a complex
network of continuous sheets and tubules, extending from the nuclear envelope (NE) to the …

During dengue virus infection of host cells, intracellular membranes are rearranged into
distinct subcellular structures such as double-membrane vesicles, convoluted membranes …