Fluid mechanics of heart valves and their replacements
As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …
Principles of TAVR valve design, modelling, and testing
Introduction: Transcatheter aortic valve replacement (TAVR) has emerged as an effective
minimally-invasive alternative to surgical valve replacement in medium-to high-risk, elderly …
minimally-invasive alternative to surgical valve replacement in medium-to high-risk, elderly …
Implantation of a tissue-engineered tubular heart valve in growing lambs
J Reimer, Z Syedain, B Haynie, M Lahti, J Berry… - Annals of biomedical …, 2017 - Springer
Current pediatric heart valve replacement options are suboptimal because they are
incapable of somatic growth. Thus, children typically have multiple surgeries to replace …
incapable of somatic growth. Thus, children typically have multiple surgeries to replace …
Living nano-micro fibrous woven fabric/hydrogel composite scaffolds for heart valve engineering
Regeneration and repair of injured or diseased heart valves remains a clinical challenge.
Tissue engineering provides a promising treatment approach to facilitate living heart valve …
Tissue engineering provides a promising treatment approach to facilitate living heart valve …
On the mechanics of transcatheter aortic valve replacement
Transcatheter aortic valves (TAVs) represent the latest advances in prosthetic heart valve
technology. TAVs are truly transformational as they bring the benefit of heart valve …
technology. TAVs are truly transformational as they bring the benefit of heart valve …
[HTML][HTML] Evaluation of an aortic valve prosthesis: Fluid-structure interaction or structural simulation?
Bio-inspired polymeric heart valves (PHVs) are excellent candidates to mimic the structural
and the fluid dynamic features of the native valve. PHVs can be implanted as prosthetic …
and the fluid dynamic features of the native valve. PHVs can be implanted as prosthetic …
Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Applications: In Vitro Hemodynamic Study
Transcatheter aortic valve replacement (TAVR) is a minimally-invasive approach for treating
severe aortic stenosis. All clinically-used TAVR valves to date utilize chemically-fixed …
severe aortic stenosis. All clinically-used TAVR valves to date utilize chemically-fixed …
The future of heart valve replacement: recent developments and translational challenges for heart valve tissue engineering
ES Fioretta, PE Dijkman, MY Emmert… - Journal of tissue …, 2018 - Wiley Online Library
Heart valve replacement is often the only solution for patients suffering from valvular heart
disease. However, currently available valve replacements require either life‐long …
disease. However, currently available valve replacements require either life‐long …
Recent advances in biological macromolecule based tissue-engineered composite scaffolds for cardiac tissue regeneration applications
Tissue engineering has become a primary research topic for the treatment of diseased or
damaged cardiac tissue, which is a global healthcare concern. Current tissue engineering …
damaged cardiac tissue, which is a global healthcare concern. Current tissue engineering …
Evaluating medical device and material thrombosis under flow: current and emerging technologies
Although blood-contacting medical devices are used widely, blood clot formation
(thrombosis) leads to device failure and potentially catastrophic adverse thrombotic events …
(thrombosis) leads to device failure and potentially catastrophic adverse thrombotic events …