Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease

AC Boese, SC Kim, KJ Yin, JP Lee… - American Journal of …, 2017 - journals.physiology.org
Sex differences between women and men are often overlooked and underappreciated when
studying the cardiovascular system. It has been long assumed that men and women are …

[HTML][HTML] Testosterone: a vascular hormone in health and disease

DM Kelly, TH Jones - Journal of Endocrinology, 2013 - joe.bioscientifica.com
Coronary heart disease is a leading cause of premature death in men. Epidemiological
studies have shown a high prevalence of low serum testosterone levels in men with …

Sex hormones in the cardiovascular system

RL dos Santos, FB da Silva, RF Ribeiro Jr… - … molecular biology and …, 2014 - degruyter.com
Gender-associated differences in the development of cardiovascular diseases have been
described in humans and animals. These differences could explain the low incidence of …

Fetoplacental vasculature as a model to study human cardiovascular endocrine disruption

M Lorigo, E Cairrao - Molecular aspects of medicine, 2022 - Elsevier
Increasing evidence has associated the exposure of endocrine-disrupting chemicals (EDCs)
with the cardiovascular (CV) system. This exposure is particularly problematic in a sensitive …

The dark side of testosterone deficiency: III. Cardiovascular disease

AM Traish, F Saad, RJ Feeley, A Guay - Journal of andrology, 2009 - Wiley Online Library
A considerable body of evidence exists suggesting that androgen deficiency contributes to
the onset, progression, or both of cardiovascular disease (CVD). The aim of this review is to …

Evaluation of the interaction of sex hormones and cardiovascular function and health

MMA Willemars, M Nabben, JAJ Verdonschot… - Current heart failure …, 2022 - Springer
Abstract Purpose of Review Sex hormones drive development and function of reproductive
organs or the development of secondary sex characteristics but their effects on the …

[HTML][HTML] The effect of testosterone on cardiovascular disease and cardiovascular risk factors in men: a review of clinical and preclinical data

H Kaur, GH Werstuck - CJC open, 2021 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death worldwide. The effects of
testosterone, the primary male sex hormone, on cardiovascular risk have been of special …

The effects of testosterone on risk factors for, and the mediators of, the atherosclerotic process

TH Jones, F Saad - Atherosclerosis, 2009 - Elsevier
It is becoming increasingly evident that the low serum levels of testosterone experienced by
aging men are associated with increased all-cause mortality from CHD and other vascular …

Vascular mechanisms of testosterone: the non-genomic point of view

M Lorigo, M Mariana, MC Lemos, E Cairrao - The Journal of steroid …, 2020 - Elsevier
Testosterone (T) is the predominant endogenous androgen in the bloodstream. At the
vascular level, T presents genomic and non-genomic effects, and both effects may overlap …

[HTML][HTML] Disrupting effects of the emerging contaminant octylmethoxycinnamate (OMC) on human umbilical artery relaxation

M Lorigo, C Mangana, E Cairrao - Environmental Pollution, 2023 - Elsevier
Cardiovascular diseases (CVD) represent the number one cause of death worldwide. The
vascular endothelium may play a role in the pathophysiology of CVD diseases …