Genomic perspectives on the evolution and spread of bacterial pathogens
SD Bentley, J Parkhill - … of the Royal Society B: Biological …, 2015 - royalsocietypublishing.org
Since the first complete sequencing of a free-living organism, Haemophilus influenzae,
genomics has been used to probe both the biology of bacterial pathogens and their …
genomics has been used to probe both the biology of bacterial pathogens and their …
Outbreak dynamics of foodborne pathogen Vibrio parahaemolyticus over a seventeen year period implies hidden reservoirs
Controlling foodborne diseases requires robust outbreak detection and a comprehensive
understanding of outbreak dynamics. Here, by integrating large-scale phylogenomic …
understanding of outbreak dynamics. Here, by integrating large-scale phylogenomic …
[PDF][PDF] Emergence, ecology and dispersal of the pandemic generating Vibrio cholerae lineage
Although cholera is an ancient disease that first arose at least half a millennium ago, it
remains a major health threat globally. Its pandemic form is caused by strains from a single …
remains a major health threat globally. Its pandemic form is caused by strains from a single …
Vibrio cholerae high cell density quorum sensing activates the host intestinal innate immune response
BE Jugder, JH Batista, JA Gibson, PM Cunningham… - Cell reports, 2022 - cell.com
Quorum sensing fundamentally alters the interaction of Vibrio cholerae with aquatic
environments, environmental hosts, and the human intestine. At high cell density, the …
environments, environmental hosts, and the human intestine. At high cell density, the …
FAVITES: simultaneous simulation of transmission networks, phylogenetic trees and sequences
Motivation The ability to simulate epidemics as a function of model parameters allows
insights that are unobtainable from real datasets. Further, reconstructing transmission …
insights that are unobtainable from real datasets. Further, reconstructing transmission …
Activation of Vibrio cholerae quorum sensing promotes survival of an arthropod host
Vibrio cholerae colonizes the human terminal ileum to cause cholera, and the arthropod
intestine and exoskeleton to persist in the aquatic environment. Attachment to these surfaces …
intestine and exoskeleton to persist in the aquatic environment. Attachment to these surfaces …
Toxigenic Vibrio cholerae evolution and establishment of reservoirs in aquatic ecosystems
The spread of cholera in the midst of an epidemic is largely driven by direct transmission
from person to person, although it is well-recognized that Vibrio cholerae is also capable of …
from person to person, although it is well-recognized that Vibrio cholerae is also capable of …
Phenotypic analysis reveals that the 2010 Haiti cholera epidemic is linked to a hypervirulent strain
ABSTRACT Vibrio cholerae O1 El Tor strains have been responsible for pandemic cholera
since 1961. These strains have evolved over time, spreading globally in three separate …
since 1961. These strains have evolved over time, spreading globally in three separate …
A globally distributed mobile genetic element inhibits natural transformation of Vibrio cholerae
AB Dalia, KD Seed, SB Calderwood… - Proceedings of the …, 2015 - National Acad Sciences
Natural transformation is one mechanism of horizontal gene transfer (HGT) in Vibrio
cholerae, the causative agent of cholera. Recently, it was found that V. cholerae isolates …
cholerae, the causative agent of cholera. Recently, it was found that V. cholerae isolates …
The impact of selection, gene conversion, and biased sampling on the assessment of microbial demography
Recent studies have linked demographic changes and epidemiological patterns in bacterial
populations using coalescent-based approaches. We identified 26 studies using skyline …
populations using coalescent-based approaches. We identified 26 studies using skyline …