[HTML][HTML] The status of hepatitis B control in the African region

L Breakwell, C Tevi-Benissan, L Childs… - The Pan African …, 2017 - ncbi.nlm.nih.gov
Abstract The World Health Organization (WHO) African Region has approximately 100
million people with chronic hepatitis B virus (HBV) infection. This review describes the status …

A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action

J Mokaya, AL McNaughton, MJ Hadley… - PLoS neglected …, 2018 - journals.plos.org
International sustainable development goals for the elimination of viral hepatitis as a public
health problem by 2030 highlight the pressing need to optimize strategies for prevention …

Mapping hepatitis B virus genotypes on the African continent from 1997 to 2021: A systematic review with meta-analysis

HM Kafeero, D Ndagire, P Ocama, CD Kato… - Scientific Reports, 2023 - nature.com
Hepatitis B virus (HBV) has ten genotypes (A–J) and over 40 sub-genotypes based on the
divergence of≥ 8% and 4 to< 8% in the complete genome respectively. These genotypes …

[HTML][HTML] Genetic diversity of hepatitis viruses in West-African countries from 1996 to 2018

M Assih, AK Ouattara, B Diarra, AT Yonli… - World journal of …, 2018 - ncbi.nlm.nih.gov
The severity of hepatic pathology and the response to treatment depend on the hepatitis
virus genotype in the infected host. The objective of this review was to determine the …

Patterns of hepatitis b virus immune escape and pol/rt mutations across clinical cohorts of patients with genotypes a, e and occult hepatitis b infection in Nigeria: A …

OG Osasona, OO Oguntoye, AO Arowosaye… - Virulence, 2023 - Taylor & Francis
Hepatitis B virus (HBV) immune escape and Pol/RT mutations account for HBV
immunoprophylactic, therapeutic, and diagnostic failure globally. Little is known about …

In silico prediction and in vitro verification of a novel multi-epitope antigen for HBV detection

S Khalili, MJ Rasaee, SL Mousavi, J Amani… - Molecular Genetics …, 2017 - Springer
After years of ongoing endeavors for HBV infection prognosis, diagnosis and treatment, it
still remains a major health problem worldwide. About 400 million chronic carriers and an …

Pattern of prevalent hepatitis B virus genotypes in Zaria, Nigeria

AE Ahmad, AG Bakari, BOP Musa… - Nigerian …, 2019 - journals.lww.com
Background: Hepatitis B virus (HBV) is hyperendemic in Nigeria. Available literature reveal
genotype E as being predominant in West Africa. This study aimed at identifying the current …

Detection of Q129H immune escape mutation in apparently healthy hepatitis B virus carriers in southwestern Nigeria

OA Adesina, OA Akanbi, OO Opaleye, MO Japhet… - Viruses, 2021 - mdpi.com
As the global effort to eradicate hepatitis B continues, immune escape mutations (IEMs) and
drug resistance mutations (DRMs) affecting its diagnosis, treatment, and prevention are …

Patterns of serologic markers of hepatitis B virus infection and the risk of transmission among pregnant women in southwestern Nigeria

IM Ifeorah, AS Bakarey, MO Adewumi… - … of Immunoassay and …, 2017 - Taylor & Francis
Hepatitis B virus (HBV) infection is a major health concern in developing countries that has a
high morbidity and mortality rate. Vertical transmission of HBV from mother to child has been …

Acute hepatitis E virus infection in two geographical regions of Nigeria

IM Ifeorah, TOC Faleye, AS Bakarey… - Journal of …, 2017 - Wiley Online Library
Hepatitis E virus (HEV) remains a major public health concern in resource limited regions of
the world. Yet data reporting is suboptimal and surveillance system is inadequate. In …