In the adult mammalian hippocampus, new neurons arise from stem and progenitor cell
division, in a process known as adult neurogenesis. Adult-generated neurons are sensitive …

Parvalbumin-expressing (PV+) interneurons play a key role in the maturation and
synchronization of cortical circuitry and alterations in these inhibitory neurons, especially in …

Neuroinflammation is a pathophysiological condition associated with damage to the nervous
system. Maternal immune activation and early immune activation have adverse effects on …

Collagen scaffolds possess a three-dimensional porous structure that provides sufficient
space for cell growth and proliferation, the passage of nutrients and oxygen, and the …

During immature stages, adult-born neurons pass through critical periods for survival and
plasticity. It is generally assumed that by 2 months of age adult-born neurons are mature and …

The maintenance of axons for the lifetime of an organism requires an axonal cytoskeleton
that is robust but also flexible to adapt to mechanical challenges and to support plastic …

This work provides evidence of the presence of immature neurons in the human brain,
specifically in the layer II of the cerebral cortex. Using surgical samples from epileptic …

Immature neurons are maintained in cortical regions of the adult mammalian brain. In
rodents, many of these immature neurons can be identified in the piriform cortex based on …

Despite the central role of Rho GTPases in neuronal development, their functions in adult
hippocampal neurogenesis remain poorly explored. Here, by using a retrovirus-based loss …

The dentate gyrus (DG) of the hippocampus is evolutionarily conserved as one of the few
sites of adult neurogenesis in mammals. Although there is clear evidence that neurogenesis …