[HTML][HTML] Recent progress in drug delivery

C Li, J Wang, Y Wang, H Gao, G Wei, Y Huang… - … pharmaceutica sinica B, 2019 - Elsevier
Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

[HTML][HTML] Stimuli-responsive transdermal microneedle patches

P Makvandi, R Jamaledin, G Chen… - Materials Today, 2021 - Elsevier
Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

Nanoenzyme-reinforced injectable hydrogel for healing diabetic wounds infected with multidrug resistant bacteria

S Wang, H Zheng, L Zhou, F Cheng, Z Liu, H Zhang… - Nano …, 2020 - ACS Publications
Diabetic wound healing remains a critical challenge due to its vulnerability to multidrug-
resistant (MDR) bacterial infection, as well as the hyperglycemic and oxidative wound …

Wet‐adhesive on‐skin sensors based on metal–organic frameworks for wireless monitoring of metabolites in sweat

X Yang, J Yi, T Wang, Y Feng, J Wang, J Yu… - Advanced …, 2022 - Wiley Online Library
Metal–organic frameworks (MOFs) with well‐defined porous structures and tailored
functionalities have been widely used in chemical sensing. However, the integration of …

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

J Yu, J Wang, Y Zhang, G Chen, W Mao, Y Ye… - Nature biomedical …, 2020 - nature.com
Glucose-responsive insulin delivery systems that mimic pancreatic endocrine function could
enhance health and improve quality of life for people with type 1 and type 2 diabetes with …

Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment

LH Fu, C Qi, J Lin, P Huang - Chemical Society Reviews, 2018 - pubs.rsc.org
Glucose oxidase (GOx) is an endogenous oxido-reductase that is widely distributed in living
organisms. Over recent years, GOx has attracted increasing interest in the biomedical field …

Glucose oxidase, an enzyme “Ferrari”: Its structure, function, production and properties in the light of various industrial and biotechnological applications

JA Bauer, M Zámocká, J Majtán, V Bauerová-Hlinková - Biomolecules, 2022 - mdpi.com
Glucose oxidase (GOx) is an important oxidoreductase enzyme with many important roles in
biological processes. It is considered an “ideal enzyme” and is often called an oxidase …

Cryomicroneedles for transdermal cell delivery

H Chang, SWT Chew, M Zheng, DCS Lio… - Nature Biomedical …, 2021 - nature.com
Cell therapies for the treatment of skin disorders could benefit from simple, safe and efficient
technology for the transdermal delivery of therapeutic cells. Conventional cell delivery by …

Biocatalytic cascades operating on macromolecular scaffolds and in confined environments

M Vázquez-González, C Wang, I Willner - Nature Catalysis, 2020 - nature.com
Biocatalytic cascades guide complex, efficient and selective intracellular transformations.
These unique features originate from the spatial organization of the biocatalysts in confined …

A swellable microneedle patch to rapidly extract skin interstitial fluid for timely metabolic analysis

H Chang, M Zheng, X Yu, A Than, RZ Seeni… - Advanced …, 2017 - Wiley Online Library
Skin interstitial fluid (ISF) is an emerging source of biomarkers for disease diagnosis and
prognosis. Microneedle (MN) patch has been identified as an ideal platform to extract ISF …