Mechanisms underlying the protective effects of mesenchymal stem cell-based therapy
XL Fan, Y Zhang, X Li, QL Fu - Cellular and molecular life sciences, 2020 - Springer
Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …
Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration
DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
Stem cell-derived exosomes as nanotherapeutics for autoimmune and neurodegenerative disorders
To dissect therapeutic mechanisms of transplanted stem cells and develop exosome-based
nanotherapeutics in treating autoimmune and neurodegenerative diseases, we assessed …
nanotherapeutics in treating autoimmune and neurodegenerative diseases, we assessed …
Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on …
S Viswanathan, Y Shi, J Galipeau, M Krampera… - Cytotherapy, 2019 - Elsevier
Abstract The International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal
Cell (ISCT MSC) committee offers a position statement to clarify the nomenclature of …
Cell (ISCT MSC) committee offers a position statement to clarify the nomenclature of …
Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes
Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
differentiate into several cell types. MSC‐based therapy has emerged as a promising …
Insights into the secretome of mesenchymal stem cells and its potential applications
S Eleuteri, A Fierabracci - International journal of molecular sciences, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) have regenerative, immunoregulatory properties and can
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …
be easily isolated and expanded in vitro. Despite being a powerful tool for clinical …
[HTML][HTML] Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis
S Cosenza, K Toupet, M Maumus, P Luz-Crawford… - Theranostics, 2018 - ncbi.nlm.nih.gov
Objectives: Mesenchymal stem cells (MSCs) release extracellular vesicles (EVs) that display
a therapeutic effect in inflammatory disease models. Although MSCs can prevent arthritis …
a therapeutic effect in inflammatory disease models. Although MSCs can prevent arthritis …
The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity
Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of clinical medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …
The therapeutic potential of mesenchymal stromal cells for regenerative medicine: current knowledge and future understandings
M Merimi, R El-Majzoub, L Lagneaux… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent decades, research on the therapeutic potential of progenitor cells has advanced
considerably. Among progenitor cells, mesenchymal stromal cells (MSCs) have attracted …
considerably. Among progenitor cells, mesenchymal stromal cells (MSCs) have attracted …
Exosome and mesenchymal stem cell cross-talk in the tumor microenvironment
TL Whiteside - Seminars in immunology, 2018 - Elsevier
Mesenchymal stem cells (MSCs) are a major component of the tumor microenvironment
(TME) and play a key role in promoting tumor progression. The tumor uses exosomes to co …
(TME) and play a key role in promoting tumor progression. The tumor uses exosomes to co …