Bilirubin and redox stress in age-related brain diseases

JP Llido, S Jayanti, C Tiribelli, S Gazzin - Antioxidants, 2023 - mdpi.com
Cellular redox status has a crucial role in brain physiology, as well as in pathologic
conditions. Physiologic senescence, by dysregulating cellular redox homeostasis and …

Inflammation, dopaminergic brain and bilirubin

S Jayanti, C Dalla Verde, C Tiribelli… - International Journal of …, 2023 - mdpi.com
Dopamine is a well-known neurotransmitter due to its involvement in Parkinson's disease
(PD). Dopamine is not only involved in PD but also controls multiple mental and physical …

Inflammatory liver diseases and susceptibility to sepsis

H Lu - Clinical Science, 2024 - portlandpress.com
Patients with inflammatory liver diseases, particularly alcohol-associated liver disease and
metabolic dysfunction-associated fatty liver disease (MAFLD), have higher incidence of …

Bilirubin-Induced transcriptomic imprinting in neonatal hyperbilirubinemia

JP Llido, E Fioriti, D Pascut, M Giuffrè, C Bottin… - Biology, 2023 - mdpi.com
Simple Summary Severe neonatal hyperbilirubinemia may damage the brain, leading to
motor, cognitive, and auditory abnormalities. We recently discovered that bilirubin might act …

Molecular events in brain bilirubin toxicity revisited

S Gazzin, C Bellarosa, C Tiribelli - Pediatric Research, 2024 - nature.com
The mechanisms involved in bilirubin neurotoxicity are still far from being fully elucidated.
Several different events concur to damage mainly the neurons among which inflammation …

An egg a day keeps kernicterus away

S Gazzin, C Tiribelli - Pediatric Research, 2024 - nature.com
Neonatal hyperbilirubinemia is a common occurrence in newborns, and timely and effective
management of severe neonatal hyperbilirubinemia (SNH) by phototherapy (PT), and more …

[PDF][PDF] Bilirubin-Induced Transcriptomic Imprinting in Neonatal Hyperbilirubinemia. Biology 2023, 12, 834

JP Llido, E Fioriti, D Pascut, M Giuffrè, C Bottin… - 2023 - researchgate.net
Recent findings indicated aberrant epigenetic control of the central nervous system (CNS)
development in hyperbilirubinemic Gunn rats as an additional cause of cerebellar …