Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders.
Functional dyspepsia comprises three subtypes with presumed different pathophysiology …

Although the gastrointestinal (GI) tract possesses intrinsic neural plexuses that allow a
significant degree of autonomy over GI functions, the central nervous system (CNS) provides …

Background Functional dyspepsia (FD) is one of the more common functional disorders, with
a prevalence of 10–20%. It affects the gastrointestinal tract. Methods This article is based on …

A large body of research has been dedicated to the effects of gastrointestinal peptides on
vagal afferent fibres, yet multiple lines of evidence indicate that gastrointestinal peptides …

Background Aims: Impaired accommodation of the proximal stomach to a meal has been
reported in functional dyspepsia, but its relevance to symptoms is unclear. The aim of this …

NO was first characterized in the CNS as the intercellular messenger mediating the increase
in cyclic GMP levels that follows activation of glutamate receptors (Garthwaite et al., 1988) …

Dyspeptic symptoms, defined as discomfort or pain in the upper part of the abdomen, occur
very commonly in the general population. Epidemiologic surveys suggest that 15%–20% of …

Current concepts and basic principles of neurogastroenterology in relation to functional
gastrointestinal disorders are reviewed. Neurogastroenterology is emphasized as a new …

It has been demonstrated that nitric oxide (NO) is a major inhibitory nonadrenergic,
noncholinergic (NANC) neurotransmitter in the gastrointestinal (GI) tract. NO released in …

Dyspepsia is the medical term for difficult digestion. It consists of various symptoms in the
upper abdomen, such as fullness, discomfort, early satiation, bloating, heartburn, belching …