Region-specific transcriptomic responses to obesity and diabetes in macaque hypothalamus
Y Lei, X Liang, Y Sun, T Yao, H Gong, Z Chen, Y Gao… - Cell metabolism, 2024 - cell.com
The hypothalamus plays a crucial role in the progression of obesity and diabetes; however,
its structural complexity and cellular heterogeneity impede targeted treatments. Here, we …
its structural complexity and cellular heterogeneity impede targeted treatments. Here, we …
Maternal dietary fat during lactation shapes single nucleus transcriptomic profile of postnatal offspring hypothalamus in a sexually dimorphic manner in mice
Maternal overnutrition during lactation predisposes offspring to develop metabolic diseases
and exacerbates the relevant syndromes in males more than females in later life. The …
and exacerbates the relevant syndromes in males more than females in later life. The …
Molecular and functional mapping of the neuroendocrine hypothalamus: a new era begins
TH Lee, JC Nicolas, C Quarta - Journal of Endocrinological Investigation, 2024 - Springer
Background Recent advances in neuroscience tools for single-cell molecular profiling of
brain neurons have revealed an enormous spectrum of neuronal subpopulations within the …
brain neurons have revealed an enormous spectrum of neuronal subpopulations within the …