The biological function of protein, DNA, and RNA molecules often depends on relative
movements of domains with dimensions of a few nanometers. This length scale can be …

Electron paramagnetic resonance (EPR) spectroscopy provides a variety of tools to study
structures and structural changes of large biomolecules or complexes thereof. In order to …

Pulsed electron-electron double resonance techniques such as the four-pulse double
electron-electron resonance experiment measure a dipolar evolution function of the sample …

Pulsed ESR techniques with the aid of site-directed spin labeling have proven useful in
providing unique structural information about proteins. The determination of distance …

Tikhonov regularization (TIKR) has been demonstrated as a powerful and valuable method
for the determination of distance distributions of spin-pairs in bi-labeled biomolecules …

For the synthesis of compounds 4 and 5 (Scheme 1) the procedures developed for the
synthesis of the shorter analogues 2 and 3 were used.[1] Starting from the readily available …

We review work on the paramagnetic amino acid 2, 2, 6, 6-tetramethyl-N-oxyl-4-amino-4-
carboxylic acid, TOAC, and its applications in studies of peptides and peptide synthesis …

Abstract Abstract Intrinsically disordered proteins (IDPs) form a unique protein category
characterized by the absence of a well-defined structure and by remarkable conformational …

The results of development of pulsed electron–electron double resonance (PELDOR)
method and its applications in structural studies are generalised and described …

The human a-synuclein protein (ASYN) plays a central role in the etiology of Parkinson's
disease, llI and forms fibrillar aggregates that are found in Lewy bodies and Lewy neurites in …