Update on HLA-B*15:02 Allele Associated with Adverse Drug Reactions

X Zhu, G Luo, L Zheng - Pharmacogenomics, 2024 - Taylor & Francis
HLA alleles, part of the major histocompatibility complex, are strongly associated with
adverse drug reactions (ADRs). This review focuses on HLA-B* 15: 02 and explores its …

[HTML][HTML] Accurate identification of HLA-B* 15: 02 allele by two-dimensional polymerase chain reaction

X Zhu, Y Yu, J Zhang, Y Zhan, G Luo, L Zheng - Clinica Chimica Acta, 2024 - Elsevier
Abstract Background HLA-B* 15: 02 is highly associated with carbamazepine-induced
SJS/TEN; however, there is no rapid and accurate detecting method. Here, we present a …

Economic Evaluation of HLA-B* 15: 02 Genotyping for Asian Australian Patients With Epilepsy

Y Gu, STF Shih, N Geevasinga, L Chan… - JAMA …, 2024 - jamanetwork.com
Importance The HLA-B* 15: 02 allele has been associated with an increased risk of
carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in …

Cost-effectiveness analysis of HLA-B* 15: 02 screening before treatment of epilepsy in Indonesia

E Tanoto, H Khosama, S Jehosua, SAS Sekeon… - Epilepsy & Behavior, 2024 - Elsevier
Introduction Adverse skin reactions due to drugs such as Stevens Johnson Syndrome (SJS)
and Toxic Epidermal Necrolysis (TEN) occur in 3% of people receiving anti epileptic drugs …