Cocaine is the leading cause for drug–abuse-related visits to emergency departments, most
of which are due to cardiovascular complaints. Through its diverse pathophysiological …

Thoracic aortic aneurysms involving the root and/or the ascending aorta enlarge over time
until an acute tear in the intimal layer leads to a highly fatal condition, an acute aortic …

The use of cocaine has evolved from chewing the leaves of the Erythroxylon coca bush
thousands of years ago, to purification of cocaine hydrochloride over 100 years ago and its …

Thoracic aortic dissection (TAD) is estimated to occur at a rate of 3–4 cases per 100,000
persons per year and is associated with a high mortality. Reported rates are probably …

Acute aortic syndrome (AAS) is a modern term to describe interrelated emergency aortic
conditions with similar clinical characteristics and challenges. These conditions include …

Thoracic aortic dissection (TAD) is a highly lethal vascular disease. In many patients with
TAD, the aorta progressively dilates and ultimately ruptures. Dissection formation …

The cardiovascular consequences of cocaine use are numerous and can be severe, with
mechanisms of cardiotoxicity unique to cocaine that include sympathomimetic effects …

Milroy CM & Parai JL (2011) Histopathology 59, 579–593 The histopathology of drugs of
abuse The use of drugs for recreational purposes is widespread. The drugs used can be …

Background Acute aortic dissection associated with cocaine use is rare and has been
reported predominantly as single cases or in small patient cohorts. Methods Our study …

The aorta, which has a complex intrinsic biology and sophisticated mechanical properties for
conducting the blood ejected from the left ventricle to the rest of the systemic arterial bed, is …