Animal models of obesity and diabetes mellitus
More than one-third of the worldwide population is overweight or obese and therefore at risk
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …
of developing type 2 diabetes mellitus. In order to mitigate this pandemic, safer and more …
[HTML][HTML] Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …
increased dementia risk in aging. Here we review the current literature interrogating the …
[HTML][HTML] Rhea: a transparent and modular R pipeline for microbial profiling based on 16S rRNA gene amplicons
The importance of 16S rRNA gene amplicon profiles for understanding the influence of
microbes in a variety of environments coupled with the steep reduction in sequencing costs …
microbes in a variety of environments coupled with the steep reduction in sequencing costs …
[HTML][HTML] IMNGS: a comprehensive open resource of processed 16S rRNA microbial profiles for ecology and diversity studies
I Lagkouvardos, D Joseph, M Kapfhammer, S Giritli… - Scientific reports, 2016 - nature.com
Abstract The SRA (Sequence Read Archive) serves as primary depository for massive
amounts of Next Generation Sequencing data and currently host over 100,000 16S rRNA …
amounts of Next Generation Sequencing data and currently host over 100,000 16S rRNA …
[HTML][HTML] The gut microbiota drives the impact of bile acids and fat source in diet on mouse metabolism
S Just, S Mondot, J Ecker, K Wegner, E Rath, L Gau… - Microbiome, 2018 - Springer
Background As the gut microbiota contributes to metabolic health, it is important to
determine specific diet-microbiota interactions that influence host metabolism. Bile acids and …
determine specific diet-microbiota interactions that influence host metabolism. Bile acids and …
[HTML][HTML] Gut to brain dysbiosis: mechanisms linking western diet consumption, the microbiome, and cognitive impairment
Consumption of a Western Diet (WD) that is high in saturated fat and added sugars
negatively impacts cognitive function, particularly mnemonic processes that rely on the …
negatively impacts cognitive function, particularly mnemonic processes that rely on the …
[HTML][HTML] Environmentally enriched housing conditions affect pig welfare, immune system and gut microbiota in early life
C Wen, I Van Dixhoorn, D Schokker, H Woelders… - Animal Microbiome, 2021 - Springer
Background Conventional pig housing and management conditions are associated with
gastrointestinal pathophysiology and disease susceptibility in early life. Developing new …
gastrointestinal pathophysiology and disease susceptibility in early life. Developing new …
[HTML][HTML] Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome
B Altaha, M Heddes, V Pilorz, Y Niu, E Gorbunova… - Molecular …, 2022 - Elsevier
Objective Internal clocks time behavior and physiology, including the gut microbiome, in a
circadian (∼ 24 h) manner. Mismatch between internal and external time, eg during shift …
circadian (∼ 24 h) manner. Mismatch between internal and external time, eg during shift …
[HTML][HTML] The effect of probiotics on immune responses and their therapeutic application: a new treatment option for multiple sclerosis
B Hashemi, M Abdollahi, S Abbaspour-Aghdam… - Biomedicine & …, 2023 - Elsevier
Multiple sclerosis (MS) is known as a chronic inflammatory disease (CID) that affects the
central nervous system and leads to nerve demyelination. However, the exact cause of MS …
central nervous system and leads to nerve demyelination. However, the exact cause of MS …
[HTML][HTML] Measuring locomotor activity and behavioral aspects of rodents living in the home-cage
CJMI Klein, T Budiman, JR Homberg… - Frontiers in Behavioral …, 2022 - frontiersin.org
Automatization and technological advances have led to a larger number of methods and
systems to monitor and measure locomotor activity and more specific behavior of a wide …
systems to monitor and measure locomotor activity and more specific behavior of a wide …