Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

For the treatment of systemic hypertension, pharmacological intervention in nitric oxide-
cyclic guanosine monophosphate signaling is a well-explored but unexploited option. In this …

Acute kidney injury (AKI) is a global healthcare burden attributable to high mortality and
staggering costs of dialysis. The underlying causes of AKI include hypothermia and …

Abstract Treatment of hypertension until now has been directed at inhibition of
vasoconstriction, of cardiac contractility and of blood volume regulation. Despite the arsenal …

Background: An accumulating amount of evidence has suggested that there is a contributive
role of sympathetic nervous hyperactivity in the pathogenesis of chronic kidney disease …

Endovascular revascularization is the preferred treatment for peripheral arterial disease.
Restenosis often occurs as a response to procedure-induced arterial damage. Reducing …

Diminishing ischemia-reperfusion injury (IRI) by improving kidney preservation techniques
offers great beneficial value for kidney transplant recipients. Mitochondria play an important …

Diabetes, kidney disease, and heart disease are some of the most common causes of death
and share one underlying factor: vascular disease. Complicated by oxidative (redox) stress …

The worldwide need of organs for transplantation exceeds the numbers of available and
suitable organs considerably. The shortage of organs has already resulted in measures …

The rapid global spread of SARS-CoV-2, the causative agent of COVID-19, has set off the
alarms of healthcare systems all over the world, the situation is exacerbated as no effective …